… -68 generator for making PET tracers accessible to patients. … This is a slow process for a
macromolecule such as transferrin [7… between the gallate and gallium-transferrin species. In …

… of receptor sites on the macromolecule, the orientation of the … tracer and tritiated water (THO)
was the extravascular tracer. … the cell after the gallium-transferrin complex combines with a …

Serum transferrin (sTf) plays a pivotal role in regulating iron biodistribution and homeostasis
within the body. The molecular details of sTf Fe(III) binding blood transport, and cellular …

… across and enhance the permeability of these barriers, such as … to bind to noncognate metals
to trace the biodistribution of Tf. … ranges from small molecules to macromolecular drugs and …

… Receptor-mediator endocytosis brings the iron gallium-transferrin complex inside the cell,
where an oxidoreductase reduces it in the plasma membrane to release the iron ions bound to …