Gene therapy research for kidney diseases
L Davis, F Park - Physiological Genomics, 2019 - journals.physiology.org
… of gene therapy and provide a summary of the benefits and barriers that still exist to produce
effective gene therapy strategies to treat kidney … effectiveness of AAV vectors into the kidney …
effective gene therapy strategies to treat kidney … effectiveness of AAV vectors into the kidney …
Past, present, and future of regulatory T cell therapy in transplantation and autoimmunity
M Romano, G Fanelli, CJ Albany, G Giganti… - Frontiers in …, 2019 - frontiersin.org
… or efficacy of Treg infusion isolated from kidney transplant recipients on immunosuppression
with subclinical graft inflammation. However, following the results of this pilot study new …
with subclinical graft inflammation. However, following the results of this pilot study new …
The horizon of gene therapy in modern medicine: advances and challenges
B Arjmand, B Larijani, M Sheikh Hosseini… - Cell Biology and …, 2020 - Springer
… As mentioned before, therapeutic efficacy following gene therapy has now been reported
for several inherited diseases including SCID-X1, ADA-SCID, CGD, LCA, …
for several inherited diseases including SCID-X1, ADA-SCID, CGD, LCA, …
[HTML][HTML] Gene therapy clinical trials, where do we go? An overview
… gene therapy, we reviewed current gene therapy products as well as gene therapies that may
be approved in the near future… genetic diseases, may show higher efficacy and feasibility of …
be approved in the near future… genetic diseases, may show higher efficacy and feasibility of …
Recent advances and clinical outcomes of kidney transplantation
… Although several studies have suggested the safe use of sodium glucose transport 2 (SGLT2)
inhibitors in kidney transplant recipients [128], future studies assessing their efficacy and …
inhibitors in kidney transplant recipients [128], future studies assessing their efficacy and …
IL-6 directed therapy in transplantation
CL Miller, JC Madsen - Current transplantation reports, 2021 - Springer
… shown efficacy in single-arm, pilot trials aimed at reducing HLA antibody in highly sensitized
patients awaiting kidney transplantation … In this study, 30 kidney transplant recipients with …
patients awaiting kidney transplantation … In this study, 30 kidney transplant recipients with …
Current and future prospects for gene therapy for rare genetic diseases affecting the brain and spinal cord
TL Jensen, CR Gøtzsche… - Frontiers in molecular …, 2021 - frontiersin.org
… It is likely that these gene therapy vectors could also be efficacious in genetic epilepsy
syndromes, by targeting the general disease mechanisms underlying seizure development …
syndromes, by targeting the general disease mechanisms underlying seizure development …
An update on gene therapy for lysosomal storage disorders
MS Nagree, S Scalia, WM McKillop… - … on biological therapy, 2019 - Taylor & Francis
… platforms is demonstrated, we need to begin placing deeper focus on evaluation of efficacy.
While patient-reported outcomes must be closely monitored, some attention must also be …
While patient-reported outcomes must be closely monitored, some attention must also be …
Donor-derived cell-free DNA in solid-organ transplant diagnostics: indications, limitations, and future directions
A Kataria, D Kumar, G Gupta - Transplantation, 2021 - journals.lww.com
… focuses on kidney transplants, there are several recent as well as ongoing research studies
on … Finally, cost-effectiveness studies will be needed to guide the ideal incorporation of dd-…
on … Finally, cost-effectiveness studies will be needed to guide the ideal incorporation of dd-…
New approaches for the treatment of chronic graft-versus-host disease: current status and future directions
… Herein, we present the current status and future directions of the use of these new drugs
with particular spotlight on their targeting of specific intracellular signal transduction cascades …
with particular spotlight on their targeting of specific intracellular signal transduction cascades …