… of gene therapy and provide a summary of the benefits and barriers that still exist to produce
effective gene therapy strategies to treat kidney … effectiveness of AAV vectors into the kidney …

… or efficacy of Treg infusion isolated from kidney transplant recipients on immunosuppression
with subclinical graft inflammation. However, following the results of this pilot study new …

… As mentioned before, therapeutic efficacy following gene therapy has now been reported
for several inherited diseases including SCID-X1, ADA-SCID, CGD, LCA, …

… gene therapy, we reviewed current gene therapy products as well as gene therapies that may
be approved in the near future… genetic diseases, may show higher efficacy and feasibility of …

… Although several studies have suggested the safe use of sodium glucose transport 2 (SGLT2)
inhibitors in kidney transplant recipients [128], future studies assessing their efficacy and …

… shown efficacy in single-arm, pilot trials aimed at reducing HLA antibody in highly sensitized
patients awaiting kidney transplantation … In this study, 30 kidney transplant recipients with …

… It is likely that these gene therapy vectors could also be efficacious in genetic epilepsy
syndromes, by targeting the general disease mechanisms underlying seizure development …

… platforms is demonstrated, we need to begin placing deeper focus on evaluation of efficacy.
While patient-reported outcomes must be closely monitored, some attention must also be …

… focuses on kidney transplants, there are several recent as well as ongoing research studies
on … Finally, cost-effectiveness studies will be needed to guide the ideal incorporation of dd-…

… Herein, we present the current status and future directions of the use of these new drugs
with particular spotlight on their targeting of specific intracellular signal transduction cascades …