[HTML][HTML] Generation of cardio-protective antibodies after pneumococcal polysaccharide vaccine: Early results from a randomised controlled trial
S Ren, PM Hansbro, W Srikusalanukul, JC Horvat… - Atherosclerosis, 2022 - Elsevier
Background and aims Observational studies have demonstrated that the pneumococcal
polysaccharide vaccine (PPV) is associated with reduced risk of cardiovascular events. This
may be mediated through IgM antibodies to OxLDL, which have previously been associated
with cardioprotective effects. The Australian Study for the Prevention through Immunisation
of Cardiovascular Events (AUSPICE) is a double-blind, randomised controlled trial (RCT) of
PPV in preventing ischaemic events. Participants received PPV or placebo once at baseline …
polysaccharide vaccine (PPV) is associated with reduced risk of cardiovascular events. This
may be mediated through IgM antibodies to OxLDL, which have previously been associated
with cardioprotective effects. The Australian Study for the Prevention through Immunisation
of Cardiovascular Events (AUSPICE) is a double-blind, randomised controlled trial (RCT) of
PPV in preventing ischaemic events. Participants received PPV or placebo once at baseline …
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