Recent advances in neonatal diabetes

A Dahl, S Kumar - Diabetes, Metabolic Syndrome and Obesity, 2020 - Taylor & Francis
… The genes associated with neonatal diabetes play a vital role in … findings that can be
associated with a specific genetic … all patients with neonatal diabetes due to their increased risk for …

[HTML][HTML] Neonatal diabetes mellitus

J Beltrand, K Busiah, L Vaivre-Douret, AL Fauret… - Frontiers in …, 2020 - frontiersin.org
… frequent genetic causes of neonatal diabetes mellitus with … age, patients with diabetes had
high HLA risk genotypes and … pathophysiology of more frequent adult diabetes, such as type 2 …

A review of type 2 diabetes mellitus predisposing genes

TO Yahaya, TF Salisu - Current diabetes reviews, 2020 - ingentaconnect.com
diabetes mellitus (DM) using a personalized approach in which various forms of the diseases
will be treated based on the causal gene and its pathogenesis. … The findings of the majority …

[HTML][HTML] Gestational diabetes mellitus: the genetic susceptibility behind the disease

W Wei, Y He, X Wang, G Tan, F Zhou… - Hormone and …, 2021 - thieme-connect.com
… in different functional genes associated with increased risk for … β-cells, and its variations
relate to neonatal diabetes [10]. … to elucidate the pathogenesis of GDM in greater detail. …

The role of genetics and epigenetics in the pathogenesis of gestational diabetes mellitus

J Rosik, B Szostak, F Machaj… - … of human genetics, 2020 - Wiley Online Library
risk. In this review, we provide a detailed overview of the current knowledge concerning the
influence of genetics … The results of the study conducted on 39 women suggest that the level …

[HTML][HTML] Genetics and pathophysiology of maturity-onset diabetes of the young (MODY): A Review of current trends

TO Yahaya, SB Ufuoma - Oman Medical Journal, 2020 - ncbi.nlm.nih.gov
… These findings indicate that MODY3 patients may express … , resembling permanent neonatal
diabetes mellitus. Other GCK … detect MODY variants in predisposed members and proffer …

[HTML][HTML] Genetics and epigenetics: new insight on gestational diabetes mellitus

MG Dalfrà, S Burlina, GG Del Vescovo… - Frontiers in …, 2020 - frontiersin.org
… and epigenetics in the pathophysiology of GDM and the … between variants of selected genes
and the risk of GDM. … Intriguing results were generated by a study on the genetic variants in …

Environmental and genetic contributions to diabetes

J Tremblay, P Hamet - Metabolism, 2019 - Elsevier
risk of diseases [22,23]. We cannot change the structure of our genes, but we can influence
the results of their … factors can play an important role in the pathophysiology of diabetes, with …

[HTML][HTML] Current understandings of the pathogenesis of type 1 diabetes: Genetics to environment

AM Giwa, R Ahmed, Z Omidian, N Majety… - … journal of diabetes, 2020 - ncbi.nlm.nih.gov
… We examine the potential implications of these findings with an … , Mature Onset Diabetes of
the Youth, neonatal diabetes, and … Up to 30%-50% of the genetic risk in T1D is related to HLA …

Monogenic diabetes

A Bonnefond, R Unnikrishnan, A Doria… - Nature Reviews …, 2023 - nature.com
genetic testing. Most patients with neonatal diabetes or MODY have autosomal dominant …
has revolutionized our understanding of the pathophysiology of diabetes and the genetics