… However, functional impact of cannabinoid receptor … or genetic deletion of NET would be
expected to produce a high … only able to prevent changes in osteoclastic bone resorption (101)…

… bone disease: a focus on the peripheral type 2 cannabinoid … by overexpression of cannabinoid
receptor 2 in bone marrow … Cells were maintained in Dulbecco's modified Eagle medium (…

… mainly by type 1 and 2 cannabinoid receptors (CB1R and … CB2R gene deficient mice were
characterized by age-related … compounds, and then the changes in intracellular cAMP were …

… , rare genetic skeletal disorders are associated with changes of brain … excluded, the negative
effect on bone mass was proposed to be … In contrast, centrally expressed CB1 receptors are …

… roles of type 1 and type 2 cannabinoid receptors, and it … conditions associated with changes
in endocannabinoid tone. This … in personalizing cannabinoid therapeutics based on genetic …

… selective full agonism on cannabinoid receptor type 2 (CB2R)… complications affecting structural
and functional changes in … which cannabinoids like BCP can regulate gene transcription …

… genetic variants (epistatic interactions), including novel single-nucleotide polymorphisms
(SNPs) that potentially modify the effects … receptor-1 gene is related to low bone density in male …

… type II iodothyronine deiodinase … of ablation or dysfunction of BAT and mutation of the DOCK7
gene on bone … trabecular bone loss was improved by silence of the CB1 receptors in the …

… Peak bone mass is genetically determined but can also be … and girls, and no apparent
changes in trabecular or cortical … exception of the type 2 form), at least more than 2 fractures a …

… the cannabinoid receptor 2, which has a significant role in regulating bone metabolism (…
confirmed that CNR2-deficient mice had higher trabecular bone mass by the age of 3 mo …