[HTML][HTML] Activation of anxiogenic circuits instigates resistance to diet-induced obesity via increased energy expenditure

X Xie, H Yang, JJ An, J Houtz, JW Tan, H Xu, GY Liao… - Cell metabolism, 2019 - cell.com
mice (Figure S1H). Instead, our results indicate that the increase in energy expenditure observed
in mutant mice … tolerance and insulin sensitivity (Figures 2D and 2E) and lower levels of …

Curcumin improves insulin sensitivity and increases energy expenditure in high-fat-dietinduced obese mice associated with activation of FNDC5/irisin

T Zou, S Li, B Wang, Z Wang, Y Liu, J You - Nutrition, 2021 - Elsevier
… body energy expenditure, … obesity-related pathologic factors. In accordance, our in vitro
data further indicated that Cur increased the basal oxygen consumption of IngWAT in obese mice

GIP receptor deletion in mice confers resistance to high-fat diet-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism

GA Boer, SN Keenan, PM Miotto… - American Journal of …, 2021 - journals.physiology.org
… (GIPR KO) mice are resistant to diet-induced obesity; however, the factors mediating this
effect … Plasma insulin levels were consistently higher in WT mice during the OGTT, indicating …

[HTML][HTML] Diet-induced obesity in animal models: points to consider and influence on metabolic markers

M de Moura e Dias, SA Dos Reis… - Diabetology & Metabolic …, 2021 - Springer
… diets-induced obesity models in mouse and rat published in … an increase in endotoxemia,
insulin resistance, steatosis and … of brown adipose tissue indicate greater energy expenditure, …

Characterization of inflammation and insulin resistance in high‐fat dietinduced male C57BL/6J mouse model of obesity

D Avtanski, VA Pavlov, KJ Tracey… - Animal models and …, 2019 - Wiley Online Library
… Animal models of diet-induced obesity (DIO) are commonly … balance between energy intake
and energy expenditure, as … of the animals are important factors to consider when designing …

[HTML][HTML] Effects of different diets used in diet-induced obesity models on insulin resistance and vascular dysfunction in C57BL/6 mice

P Lang, S Hasselwander, H Li, N Xia - Scientific Reports, 2019 - nature.com
… of food intake, basal metabolism and energy expenditure, with increased energy intake or
decreased physical activity being the most important factors 3 . Especially the alterations in …

[HTML][HTML] An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models

MJ Choi, SB Jung, SE Lee, SG Kang, JH Lee, MJ Ryu… - Diabetologia, 2020 - Springer
Levels of eWAT and iWAT transcripts of factors regulating adipocyte differentiation, lipolysis,
… protects against diet-induced obesity and insulin resistance in the context of HFD feeding. …

[HTML][HTML] Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure

A Kwok, I Zvetkova, S Virtue, I Luijten… - Molecular …, 2020 - Elsevier
energy expenditure, and we suggest that further study of brown adipose tissue in both
humans and micefactors [35]. However, although an increase in G6pc:Gck liver transcript …

[HTML][HTML] Macronutrient determinants of obesity, insulin resistance and metabolic health

JA Wali, SM Solon-Biet, T Freire, AE Brandon - Biology, 2021 - mdpi.com
… adiposity by increasing energy expenditure and oxidative lipid metabolism, and … insulin
sensitivity in mice [21]. Compared with native starch-fed mice, mice consuming a high resistant

Dietinduced rodent models of obesity‐related metabolic disorders—a guide to a translational perspective

I Preguiça, A Alves, S Nunes, R Fernandes… - Obesity …, 2020 - Wiley Online Library
… , among other confounding factors. This review article revisits … peripheral insulin sensitivity
and insulin resistance than mice … via modelling of diet-induced obesity with OP/OR rats. This …