[HTML][HTML] Impact of virus genetic variability and host immunity for the success of COVID-19 vaccines

WG Dos Santos - Biomedicine & Pharmacotherapy, 2021 - Elsevier
… and the newly structural proteins synthesized are then folded and … of neutralizing antiviral
T-cell and antibody immunity is … since they do not carry viral genetic material. For this reason …

Inhalable nanovaccine with biomimetic coronavirus structure to trigger mucosal immunity of respiratory tract against COVID-19

B Zheng, W Peng, M Guo, M Huang, Y Gu… - Chemical Engineering …, 2021 - Elsevier
… (I:C) mimicking viral genetic material as immune adjuvant, … in the PN component, the specific
synthesis process is the … virus replication and modulating the antiviral immune response…

Viral pathogen-induced mechanisms to antagonize mammalian interferon (IFN) signaling pathway

JM Rojas, A Alejo, V Martín, N Sevilla - Cellular and Molecular Life …, 2021 - Springer
… the traffic or synthesis of the viral ribonucleoprotein complexes [… upregulated gene in the
initial stage of the antiviral immune … for an RNA virus, so that its genetic material remains hidden …

Diverse enzymatic activities mediate antiviral immunity in prokaryotes

L Gao, H Altae-Tran, F Böhning, KS Makarova, M Segel… - Science, 2020 - science.org
… These immune components often cluster together in the host … RNA editing and retron satellite
DNA synthesis. In addition, we … by viruses, prokaryotes possess multiple antiviral defense …

[HTML][HTML] A review: Natural polysaccharides from medicinal plants and microorganisms and their anti-herpetic mechanism

Z Liu, F Niu, Y Xie, S Xie, Y Liu, Y Yang, C Zhou… - Biomedicine & …, 2020 - Elsevier
… the virus genetic material and the protein synthesis in the host; and escaping from the immune
response. … In the following sections, we will enumerate the chemical structure and antiviral

Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity

MM Hu, WR He, P Gao, Q Yang, K He, LB Cao, S Li… - Cell research, 2019 - nature.com
… the activation of these components and onset of efficient innate antiviral immune response.
… innate antiviral immunity, we examined the expression of genes involved in BA biosynthesis

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

S Nooraei, H Bahrulolum, ZS Hoseini… - Journal of …, 2021 - Springer
… and cellular immune systems are discussed in this review. … of assembled viral proteins that
lack viral genetic material and … more viral structural capsid proteins to form the final structure

Exploiting viral sensing mediated by Toll-like receptors to design innovative vaccines

R Sartorius, M Trovato, R Manco, L D'Apice… - npj Vaccines, 2021 - nature.com
… by viral pathogens to escape from immune surveillance … pathways that culminate in the
antiviral immune responses 29 . IFN … During the life cycle of viruses, the viral genetic material may …

Nanotechnology for virus treatment

J Zhou, N Krishnan, Y Jiang, RH Fang, L Zhang - Nano Today, 2021 - Elsevier
… that can be employed to promote herd immunity, antiviral vaccines can only be applied …
composition of the virusgenetic material and the structure of its genome, additional components

Propolis antiviral and immunomodulatory activity: a review and perspectives for COVID-19 treatment

N Ripari, AA Sartori, M da Silva Honorio… - Journal of Pharmacy …, 2021 - academic.oup.com
… An overview of viruses, antiviral immunity, propolis safety … is to keep the genetic information
safe until the virus reaches a … phase, and the synthesized viral proteins and nucleic acids are …