[HTML][HTML] Early-onset colorectal cancer: Current insights and future directions

CWK Wu, RN Lui - World journal of gastrointestinal oncology, 2022 - ncbi.nlm.nih.gov
… of early onset colorectal cancer is on the rise. Herein, we discuss on various risk factors that
have been implicated for these recent trends and point to where future research needs to be …

Human colorectal cancer from the perspective of mouse models

M Stastna, L Janeckova, D Hrckulak, V Kriz, V Korinek - Genes, 2019 - mdpi.com
… expression of multiple genes. The genes predominantly encode components of various
intracellular signaling cascades. In this review, we present mouse intestinal cancer models that …

Current and future colorectal cancer screening strategies

A Shaukat, TR Levin - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Colorectal cancer (CRC) is the second leading cause of cancer-related death in the world
1 . Most CRCs are slow growing, arising from precursor lesions such as adenomatous polyps …

Current status and future perspective of immune checkpoint inhibitors in colorectal cancer

C Zhou, X Cheng, S Tu - Cancer letters, 2021 - Elsevier
Colorectal cancer (CRC) is one of the most common cancers around the world, ranking third
in terms of incidence and second in terms of mortality [1]. Despite improvements in systemic …

[HTML][HTML] Epidemiology and biology of early onset colorectal cancer

A Venugopal, JM Carethers - EXCLI journal, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third leading cause of cancer-related mortality in men or …
onset colorectal cancer (eoCRC)) has recently and dramatically increased. In this review, we

Lifestyles, genetics, and future perspectives on gastric cancer in east Asian populations

H Katoh, S Ishikawa - Journal of human genetics, 2021 - nature.com
… Finally, we discuss the future perspectives of GC and its prevention in the upcoming era of
H… Based on such knowledge of the genetics of GC in the current era, the future perspectives

Updates in the field of hereditary nonpolyposis colorectal cancer

P Peltomäki, A Olkinuora… - Expert Review of …, 2020 - Taylor & Francis
… as a possible colon cancer susceptibility gene by a candidate gene approach, based on the
… a hallmark of colon cancers and the high level of expression of GALNT12 in normal colon […

Future of colorectal cancer screening: from one-size-fits-all to tailor-made

T Kortlever, M van der Vlugt, E Dekker - Frontiers in Gastroenterology, 2022 - frontiersin.org
Colorectal cancer (CRC) is the third most common cancer and the second most lethal cancer
in the world (1). In 2020, around 2 million individuals were diagnosed with CRC. Patients …

[HTML][HTML] Colon cancer: a clinician's perspective in 2019

M Ahmed - Gastroenterology research, 2020 - ncbi.nlm.nih.gov
… When we think about common preventable cancers, first thing comes to our mind is colon
cancer or CRC. In fact, CRC is now the third most common cancer diagnosis among men and …

[HTML][HTML] Surveillance and management of colorectal dysplasia and cancer in inflammatory bowel disease: Current practice and future perspectives

AM Wijnands, R Mahmoud, MWMD Lutgens… - European journal of …, 2021 - Elsevier
… Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal
cancer (CRC). Current guidelines recommend frequent surveillance colonoscopies for …