Molecular pathogenesis, targeted therapies, and future perspectives for gastric cancer
… We will then review the molecular subtypes of gastric cancer to highlight the diversity seen
in this disease. We … gastric cancer mouse models as tools to study gastric cancer molecular …
in this disease. We … gastric cancer mouse models as tools to study gastric cancer molecular …
Colorectal cancer in inflammatory bowel diseases: epidemiology and prevention: a review
E Marabotto, S Kayali, S Buccilli, F Levo, G Bodini… - Cancers, 2022 - mdpi.com
… Colorectal cancer (CRC) is one of the most serious potential complications of inflammatory
bowel diseases (IBDs). The aging of patients affected by IBDs makes this issue a challenge …
bowel diseases (IBDs). The aging of patients affected by IBDs makes this issue a challenge …
Screening for colorectal cancer: US Preventive Services Task Force recommendation statement
KW Davidson, MJ Barry, CM Mangione, M Cabana… - Jama, 2021 - jamanetwork.com
… The benefit of reducing colorectal cancer deaths by screening for colorectal cancer in adults
50 … The USPSTF appreciates the various perspectives that were shared. Although future …
50 … The USPSTF appreciates the various perspectives that were shared. Although future …
Current progress and future perspectives of neoadjuvant anti-PD-1/PD-L1 therapy for colorectal cancer
Z Yang, G Wu, X Zhang, J Gao, C Meng, Y Liu… - Frontiers in …, 2022 - frontiersin.org
… , we focus on the development of neoadjuvant anti-PD-1/PD-L1 therapy and discuss the future
perspectives … We should fully recognize the broad application prospect of immunotherapy …
perspectives … We should fully recognize the broad application prospect of immunotherapy …
Beyond microsatellite instability: evolving strategies integrating immunotherapy for microsatellite stable colorectal cancer
… study in both gastric and colorectal cancer cohorts. Thirty-six percent of ORR was observed
in the CRC cohort alone with 7.9 mPFS in pMMR tumors. Phase II REGOMUNE trial [98] with …
in the CRC cohort alone with 7.9 mPFS in pMMR tumors. Phase II REGOMUNE trial [98] with …
Microsatellite instability in colorectal cancer liquid biopsy—current updates on its potential in non-invasive detection, prognosis and as a predictive marker
… For example, a data analysis from 17 separate trials in the Adjuvant Colon Cancer End
Points (ACCENT) database had proven the potential of MSI status in predicting the outcomes/…
Points (ACCENT) database had proven the potential of MSI status in predicting the outcomes/…
The intestinal microbiota and colorectal cancer
… with both spontaneous and chemically induced colon tumorigenesis. For example, … intestinal
tumors due to a mutation in the adenomatous polyposis coli (APC) tumor-suppressor gene…
tumors due to a mutation in the adenomatous polyposis coli (APC) tumor-suppressor gene…
A potential role of IL-6/IL-6R in the development and management of colon cancer
… In this review, we aim to shed light on the role of IL-6 signaling pathway alterations in sporadic
colorectal cancer and the development of familial polyposis syndrome. Furthermore, we …
colorectal cancer and the development of familial polyposis syndrome. Furthermore, we …
Impact of genetic mutations and nutritional status on the survival of patients with colorectal cancer
MAV Cavagnari, TD Silva, MAH Pereira, LJ Sauer… - Bmc Cancer, 2019 - Springer
… The carcinogenesis, survival and prognostic of colorectal cancer patients can be influenced
by genetic mutations and nutritional status Those process involves interactions among …
by genetic mutations and nutritional status Those process involves interactions among …
Mouse models for application in colorectal cancer: understanding the pathogenesis and relevance to the human condition
… in colon tumorigenesis. Consistently, preclinical studies reported that Apc mutation can induce
spontaneous formation of colon tumors in … used for research on colon tumorigenesis [6]. …
spontaneous formation of colon tumors in … used for research on colon tumorigenesis [6]. …