[PDF][PDF] Colorectal cancer in younger adults

P Dharwadkar, TA Zaki, CC Murphy - Hematology/oncology clinics of North …, 2022 - Elsevier
… mutations in individuals with colorectal cancer. J Clin Oncol … genetic testing of patients with
young-onset colorectal cancer. … colorectal cancer risk using common genetic susceptibility loci…

The role of diet and lifestyle in early-onset colorectal cancer: a systematic review

M Puzzono, A Mannucci, S Grannò, RA Zuppardo… - Cancers, 2021 - mdpi.com
colorectal cancer and its globally increasing trend with scant literature on its pathogenesis,
we … could complement colorectal screening for early-onset colorectal cancer prevention. …

Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes

…, R Barbosa-Matos, C São José, S Sousa, I Gullo… - … of Medical Genetics, 2022 - Elsevier
… It is generally accepted that criteria analogous to the Amsterdam criteria for hereditary
non-polyposis colorectal cancer are used in countries where GC incidence is high (eg, Japan, …

Whole exome sequencing identifies genomic alterations in proximal and distal colorectal cancer

…, ZA Razak, IM Rose, I Sagap… - … In Microbes & …, 2019 - journals.hh-publisher.com
… differed in their susceptibility to screening tests, the stage at which they were diagnosed, …
and Pacific Islanders are more prone to distal colon and rectal cancers[13]. A study by Goh and …

Colorectal cancer diagnosis: the obstacles we face in determining a non-invasive test and current advances in biomarker detection

F Kamel, K Eltarhoni, P Nisar, M Soloviev - Cancers, 2022 - mdpi.com
… suppressor gene and carrying a nearly 100% risk of colon cancer … mismatch repair mechanisms
(genes involved include MLHL, … Thus, many patients do not comply with the prospect of …

Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors

P Pinzani, V D'Argenio, M Del Re… - Clinical Chemistry and …, 2021 - degruyter.com
… In this review, we summarize the currently available information concerning liquid biopsy
in breast cancer, colon cancer, lung cancer and melanoma. These promising issues still need …

[HTML][HTML] Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential

E Saus, S Iraola-Guzmán, JR Willis… - Molecular aspects of …, 2019 - Elsevier
… review we survey current knowledge on the healthy microbiome of the gut and how it is altered
in colorectal cancer … Finally, we will discuss the potential of recent developments of novel …

[HTML][HTML] Microbiota and colorectal cancer: from gut to bedside

M Silva, V Brunner, M Tschurtschenthaler - Frontiers in Pharmacology, 2021 - frontiersin.org
Colorectal cancer (CRC) is a complex condition with heterogeneous aetiology, caused by a
combination of various environmental, genetic… new perspective on possible cancer treatment …

The tumor microenvironment of colorectal cancer metastases: opportunities in cancer immunotherapy

Y Kamal, SL Schmit, HR Frost, CI Amos - Immunotherapy, 2020 - Future Medicine
… of metastasis from colon and rectal cancer to specific sites shows liver is the most common
site of metastasis (70% in colon and rectal cancer) followed … Conclusion & future perspective

Pharmacogenomics of 5-fluorouracil in colorectal cancer: review and update

P Xie, JL Mo, JH Liu, X Li, LM Tan, W Zhang, HH Zhou… - Cellular oncology, 2020 - Springer
genes and/or pathways to reverse 5-FU resistance is provided. Based on this, we suggest that
causal relationships between genes, … from a multidimensional perspective. In the design of …