… Autoimmune diseases are a diverse group of conditions characterized by aberrant B cell
and T cell reactivity to normal constituents of the host. These diseases occur widely and affect …

… the role of Treg cells in autoimmune diseases, especially how genetic anomalies such as
FOXP3 gene mutations or genetic variations such as autoimmune disease-associated single …

… ” autoimmune disorders in which genetically identical … previously active genes plays a role
in gene regulation. DNMT1 … to immune activation or autoimmune/inflammatory disease (89). …

… IRF4 in Tregs inhibited a Th2 immune response, which allowed for IL-4-… response of Th2
cells [57]. The Th2 transcription factor GATA3 in Tregs may demonstrate increased regulatory …

… contribute to the elucidation of the mechanisms and pathways whereby genetic variation
influences gene regulation and immune … in our understanding of genetic variation in amino acid …

… as key players of gene regulation in various human … diseases the immune response is
directed towards a single organ. Examples of systemic and organ-specific autoimmune diseases …

… or type I IFN-inducible gene signatures in the serum or tissues of patients with autoimmune
disorders are linked to their pathogenesis, clinical manifestations, and disease activity. Type I …

… A similar result regarding the innate immune response to infection was revealed by …
based on particular gene regulatory scenarios. A study described these genes by performing …

… complex genetic regulation of immune cells with highly selective effects on autoimmune
disease … pathways informing the design of more specific treatments for autoimmune diseases. …

… autoimmune disease (AD) depending on the misbalance between risk and protective …
immune response to an invading microorganism can alter this regulation and trigger autoimmunity […