An update on genetic frontotemporal dementia
CV Greaves, JD Rohrer - Journal of neurology, 2019 - Springer
… will discuss the recent updates in the field of genetic FTD. … the more recently discovered genes
such as TBK1 and we … We offer genetic testing in our clinic to all those with bvFTD, even in …
such as TBK1 and we … We offer genetic testing in our clinic to all those with bvFTD, even in …
Recent advances in the genetics of frontotemporal dementia
… survey of genes implicated in FTD in the last several years, we also … We then provide a broad
overview of other FTD-associated … Using gene interaction network analysis, we found that …
overview of other FTD-associated … Using gene interaction network analysis, we found that …
Genetics and molecular mechanisms of frontotemporal lobar degeneration: an update and future avenues
R Ferrari, C Manzoni, J Hardy - Neurobiology of aging, 2019 - Elsevier
… the genetic architecture of sporadic FTLD by summarizing results of genome-wide
association studies performed in FTLD … in FTLD cases; thus, we suggest to label them as “major-FTLD …
association studies performed in FTLD … in FTLD cases; thus, we suggest to label them as “major-FTLD …
Systematic review: genetic, neuroimaging, and fluids biomarkers for frontotemporal dementia across Latin America countries
C Duran-Aniotz, P Orellana, T Leon Rodriguez… - Frontiers in …, 2021 - frontiersin.org
… update and an overview of the current knowledge on genetic, … PRISMA analysis, our search
identified 21 studies on FTD and … literature comes from genetics and neuroimaging studies, …
identified 21 studies on FTD and … literature comes from genetics and neuroimaging studies, …
Frontotemporal dementia: neuropathology, genetics, neuroimaging, and treatments
K Younes, BL Miller - Psychiatric Clinics, 2020 - psych.theclinics.com
… FTD underwent multiple iterations over the years to adapt to the growing knowledge of the
clinical, genetic, neuroimaging, and pathologic understanding of FTD. … discriminant analysis, …
clinical, genetic, neuroimaging, and pathologic understanding of FTD. … discriminant analysis, …
Genetic forms of frontotemporal lobar degeneration: current diagnostic approach and new directions in therapeutic strategies
L Sellami, D Saracino, I Le Ber - Revue neurologique, 2020 - Elsevier
… In this review, we will focus on the major FTLD genes, their … We will also give an overview
on the ongoing clinical trials … Dementia Subjects) [85], Predict-PGRN [86] and PREV-DEMALS […
on the ongoing clinical trials … Dementia Subjects) [85], Predict-PGRN [86] and PREV-DEMALS […
Recent updates on the genetics of amyotrophic lateral sclerosis and frontotemporal dementia
L Kirola, A Mukherjee, M Mutsuddi - Molecular Neurobiology, 2022 - Springer
… play a pleiotropic effect on ALS-FTD and other diseases such as … trials on stem cell and
gene-based therapies. This review discusses the possible genetic models of ALS and FTD, the …
gene-based therapies. This review discusses the possible genetic models of ALS and FTD, the …
The use of biomarkers and genetic screening to diagnose frontotemporal dementia: evidence and clinical implications
H Gossye, C Van Broeckhoven… - Frontiers in …, 2019 - frontiersin.org
… • Genetic testing of known causal AD and FTD genes was … age at onset and disease duration
(overview in Table 1). … the neuropathological correlation expected with each mutated gene, …
(overview in Table 1). … the neuropathological correlation expected with each mutated gene, …
Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases
…, J Graff‐Radford, N Graff‐Radford, I Grant… - Alzheimer's & …, 2020 - Wiley Online Library
… , and C9orf72, we also identified variants in less common FTD genes. Two … studies, we
cannot speculate about the frequency of these genes in our familial series, as these are expected …
cannot speculate about the frequency of these genes in our familial series, as these are expected …
Tracking disease progression in familial and sporadic frontotemporal lobar degeneration: recent findings from ARTFL and LEFFTDS
HJ Rosen, BF Boeve, AL Boxer - Alzheimer's & Dementia, 2020 - Wiley Online Library
… 1 INTRODUCTION … with FTLD and identifying new genes, (2) developing FTLD biomarkers
for diagnosis and disease progression, (3) creating an international FTLD clinical trials …
for diagnosis and disease progression, (3) creating an international FTLD clinical trials …