Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19

MJ Corley, APS Pang, K Dody, PA Mudd… - Journal of leukocyte …, 2021 - academic.oup.com
… Here, we examined genome-wide DNA methylation (DNAm) profiles of peripheral blood
mononuclear cells from 9 terminally-ill, critical COVID-19 patients with confirmed SARS-CoV-2 …

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain …

CCY Wong, RG Smith, E Hannon… - Human molecular …, 2019 - academic.oup.com
… between DNA methylation difference (X-axis) and gene … in DNA methylation across an
imprinted gene cluster within … cases profiled in this study, we quantified DNA methylation in …

DNA methylation profiling: an emerging paradigm for cancer diagnosis

A Papanicolau-Sengos, K Aldape - Annual Review of Pathology …, 2022 - annualreviews.org
DNA methylation profiling is an additional emerging tool that … Genome-wide interrogation of
DNA methylation signatures, in … Tumor DNA methylation profiling has led to the identification …

DNA methylation profiling of human hepatocarcinogenesis

G Hernandez‐Meza, J von Felden… - …, 2021 - Wiley Online Library
DNA methylation changes across the different histological stages of human
hepatocarcinogenesis. To do so, we analyzed genomewide DNA methylation profiles … and …

Diagnostic utility of genome-wide DNA methylation testing in genetically unsolved individuals with suspected hereditary conditions

E Aref-Eshghi, EG Bend, S Colaiacovo… - The American Journal of …, 2019 - cell.com
… In the present study, using genome-wide DNA methylation analysis, we develop a computational
model for the concurrent identification of 14 ND/CA syndromes currently known to be …

Clinical epigenomics: genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders

B Sadikovic, MA Levy, J Kerkhof, E Aref-Eshghi… - Genetics in …, 2021 - nature.com
… We describe the clinical implementation of genome-wide DNA methylation analysis in rare
disorders across the EpiSign diagnostic laboratory network and the assessment of results …

Gene set enrichment analysis for genome-wide DNA methylation data

J Maksimovic, A Oshlack, B Phipson - Genome Biology, 2021 - Springer
… Here we present GOmeth and GOregion to perform gene set analysis in the context of DNA
methylation array data for differential methylation of CpG sites and regions, respectively. The …

Distinct epigenetic features of tumor-reactive CD8+ T cells in colorectal cancer patients revealed by genome-wide DNA methylation analysis

R Yang, S Cheng, N Luo, R Gao, K Yu, B Kang… - Genome biology, 2020 - Springer
… Our in-depth methylation profiling identified the specific demethylation status … broad but
undefined effect on the genome [39]. Advances in techniques for manipulating DNA methylation

DNA methylation in nasal epithelium, atopy, and atopic asthma in children: a genome-wide study

E Forno, T Wang, C Qi, Q Yan, CJ Xu… - The lancet Respiratory …, 2019 - thelancet.com
… We aimed to identify DNA methylation profiles that are … methylation profiles in airway
epithelium that are associated with atopy and atopic asthma in children, and a nasal methylation

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… emerging DNA methylationgenome-wide DNA methylation profiling techniques. These
approaches hold promise for facilitating our comprehensive understanding of DNA methylation