Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas

Y Tian, E Arai, S Makiuchi, N Tsuda, J Kuramoto… - Journal of Cancer …, 2020 - Springer
… In this study, genome-wide DNA methylation analysis using … important tumor-related genes
showing DNA hypomethylation and … Genome-wide DNA methylation analysis using human …

[HTML][HTML] Colon cancer-specific diagnostic and prognostic biomarkers based on genome-wide abnormal DNA methylation

Y Wang, M Zhang, X Hu, W Qin, H Wu, M Wei - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
… Through conditional screening and machine learning with a … The accumulation of aberrantly
methylated DNA sites in … We downloaded DNA methylation, gene expression and COAD …

Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma

Y Xi, Y Lin, W Guo, X Wang, H Zhao, C Miao… - … and Targeted Therapy, 2022 - nature.com
… This study investigates aberrant DNA methylations as … DMCs with a variety of gene
expression alterations as well as … s t test for gene expression and Wilcoxon signed-rank test for …

[HTML][HTML] Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA

RA Hlady, X Zhao, X Pan, JD Yang, F Ahmed… - Theranostics, 2019 - ncbi.nlm.nih.gov
… The frequency and number of aberrantly methylated genes … with in an increase in gene
expression in HCC relative to … non-invasive clinical test screening substrate, leads to more …

Diagnostic utility of genome-wide DNA methylation testing in genetically unsolved individuals with suspected hereditary conditions

E Aref-Eshghi, EG Bend, S Colaiacovo… - The American Journal of …, 2019 - cell.com
… involved genes clinically or functionally linked to the subjects’ phenotypes. This study
demonstrates that genomic DNA methylationtesting in the routine clinical assessment of ND/CAs. …

Genome-wide DNA methylation profiles of low-and high-grade adenoma reveals potential biomarkers for early detection of colorectal carcinoma

J Fan, J Li, S Guo, C Tao, H Zhang, W Wang… - Clinical …, 2020 - Springer
DNA methylation and gene expression of ADHFE1. c Relationship between DNA methylation
and gene expression … , SEPT9 has been applied for colon cancers screening [39]. Actually …

Genome-wide identification and characterization of DNA methylation and long non-coding RNA expression in gastric cancer

P Song, L Wu, W Guan - Frontiers in genetics, 2020 - frontiersin.org
… lncRNAs regulated by aberrant DNA methylation that have … Additionally, lncRNAs showing
aberrant DNA methylation … to compare DNA methylation and gene expression patterns …

Genome-wide DNA methylation profile of early-onset endometrial cancer: its correlation with genetic aberrations and comparison with late-onset endometrial cancer

T Makabe, E Arai, T Hirano, N Ito, Y Fukamachi… - …, 2019 - academic.oup.com
… instability and aberrant expression of tumor-related genes (9… resolution genome-wide DNA
methylation screening using … a result of the differences in the gene expression profiles. In fact, …

Genome-wide analysis of the hypoxia-related DNA methylation-driven genes in lung adenocarcinoma progression

H Li, L Tong, H Tao, Z Liu - Bioscience reports, 2020 - portlandpress.com
… In addition, DNA methylation can inhibit gene expression by … We found that hypoxia-related
aberrantly methylated DEGs … To further screen the key genes in the hypoxia-related LUAD …

Integrative analysis of DNA methylation and gene expression identified cervical cancer-specific diagnostic biomarkers

W Xu, M Xu, L Wang, W Zhou, R Xiang, Y Shi… - Signal transduction and …, 2019 - nature.com
… By using a systemic screening method and a machine-learning approach, we identified
four … by aberrant DNA methylation was observed in breast cancer cells. The remaining three …