Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease
J Stevenson-Hoare, A Heslegrave, G Leonenko… - Brain, 2023 - academic.oup.com
… a genome-wide association study for association of disease … Genome-wide association
studies (GWAS) of CSF … for clinical AD diagnosis in our cohort (over and above commonly used …
studies (GWAS) of CSF … for clinical AD diagnosis in our cohort (over and above commonly used …
[HTML][HTML] Microglial activation, tau pathology, and neurodegeneration biomarkers predict longitudinal cognitive decline in Alzheimer's disease continuum
YH Chen, RR Lin, HF Huang, YY Xue… - Frontiers in Aging …, 2022 - frontiersin.org
… in cerebrospinal fluid (CSF) and plasma to predict longitudinal cognition status using
Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. … in genome-wide association studies …
Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. … in genome-wide association studies …
Identifying potential genetic epistasis implicated in Alzheimer's disease via detection of SNP-SNP interaction on quantitative trait CSF Aβ42
J Li, D Chen, H Liu, Y Xi, H Luo, Y Wei, J Liu… - Neurobiology of …, 2024 - Elsevier
… Although genome-wide association studies have identified … genome-wide SNP-SNP interaction
on cerebrospinal fluid Aβ 42 … a genome-wide epistasis detection study in the ADNI cohort …
on cerebrospinal fluid Aβ 42 … a genome-wide epistasis detection study in the ADNI cohort …
Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia
… Genome-wide association studies have successfully … AD CSF biomarkers (Aβ42, t-tau, p-tau
and t-tau/ Aβ42 ratio) … validation cohorts (ADC cohort: 4 rs4637258, P = 0.01; ADNI cohort …
and t-tau/ Aβ42 ratio) … validation cohorts (ADC cohort: 4 rs4637258, P = 0.01; ADNI cohort …
A GPU-based approach for detecting genome-wide SNP-SNP interactions of quantitative trait in ADNI cohorts
Q Zhang, H Liu, L Ao, H Liang… - 2022 IEEE International …, 2022 - ieeexplore.ieee.org
… The phenotype used in this paper is CSF Qt. Using … the variance explained by interaction
term on T-tau/Aβ42. The … ., “Genome-wide association and interaction studies of CSF …
term on T-tau/Aβ42. The … ., “Genome-wide association and interaction studies of CSF …
Blood and cerebrospinal fluid biomarkers for Alzheimer's disease: from clinical to preclinical cohorts
A Keshavan - 2019 - discovery.ucl.ac.uk
… contribution to AD risk was identified by genome-wide … Later studies have shown that the
CSF Aβ42/40 ratio may be … of rates of change of CSF biomarkers in ADNI. Reproduced with …
CSF Aβ42/40 ratio may be … of rates of change of CSF biomarkers in ADNI. Reproduced with …
Associations of alcohol consumption with cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact older adults: the CABLE study
ZT Wang, KY Li, CC Tan, W Xu… - Journal of …, 2021 - content.iospress.com
… AD biomarkers, we examined the interaction effects (… higher biomarker ratios (CSF pTau/Aβ
42 , p = 0.0066; CSF tTau/… of drinking and CSF AD biomarkers (p-tau/Aβ42 and t-tau/Aβ42) (…
42 , p = 0.0066; CSF tTau/… of drinking and CSF AD biomarkers (p-tau/Aβ42 and t-tau/Aβ42) (…
Key inflammatory pathway activations in the MCI stage of Alzheimer's disease
… both cohorts and correlated with AD biomarkers (CSF Aβ42, … .3, 10, 11 In addition,
genome-wide association studies have … Subject demographics of the discovery and ADNI cohorts …
genome-wide association studies have … Subject demographics of the discovery and ADNI cohorts …
Association of rs2072446 in the NGFR gene with the risk of Alzheimer's disease and amyloid‐β deposition in the brain
CY He, ZT Wang, YY Shen, AY Shi… - CNS Neuroscience …, 2022 - Wiley Online Library
… Genome-wide association studies (GWAS) have identified more than 50 genetic risk factors
… study on the genome-wide network-based pathway analysis of CSF t-tau/Aβ42 ratio in the …
… study on the genome-wide network-based pathway analysis of CSF t-tau/Aβ42 ratio in the …
[PDF][PDF] Exploring brain structure and blood metabolic profiles using Alzheimer's pathway specific polygenic risk scores
J Harrison - 2021 - core.ac.uk
… by two large population cohort studies, the Avon Longitudinal … E (APOE), genome wide
association studies (GWAS) have … MRI techniques with cerebrospinal fluid and neuroradiology …
association studies (GWAS) have … MRI techniques with cerebrospinal fluid and neuroradiology …