Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation
… paused Pol II, nucleosomes as obstacles to elongation, and potential roles of pausing in
defining the precision and dynamics … Interaction with the NELF complex constrains paused Pol II …
defining the precision and dynamics … Interaction with the NELF complex constrains paused Pol II …
Regulation of promoter proximal pausing of RNA polymerase II in metazoans
R Dollinger, DS Gilmour - Journal of molecular biology, 2021 - Elsevier
… the pause and governing the dynamics of pause stability and … that relies on the interplay
between intrinsic and extrinsic … A later genome-wide analysis of promoter elements in the …
between intrinsic and extrinsic … A later genome-wide analysis of promoter elements in the …
TFIID enables RNA polymerase II promoter-proximal pausing
… To circumvent these issues, we sought to reconstitute RNAPII promoter-proximal pausing …
Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing…
Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing…
Genome-wide analyses of chromatin interactions after the loss of Pol I, Pol II, and Pol III
Y Jiang, J Huang, K Lun, B Li, H Zheng, Y Li, R Zhou… - Genome biology, 2020 - Springer
… Blocking of the transcription elongation enhances Cohesin … indicated that Pol II transcription
restrains the dynamics of … the Pol I-, Pol II-, and Pol III-binding and interaction hotspots …
restrains the dynamics of … the Pol I-, Pol II-, and Pol III-binding and interaction hotspots …
NELF regulates a promoter-proximal step distinct from RNA Pol II pause-release
Y Aoi, ER Smith, AP Shah, EJ Rendleman, SA Marshall… - Molecular cell, 2020 - cell.com
… NELF functioning in early elongation complexes distinct from RNA Pol II pause-release. …
Despite the pervasiveness of promoter-proximal pausing in metazoans and the abundant …
Despite the pervasiveness of promoter-proximal pausing in metazoans and the abundant …
Causes and consequences of RNA polymerase II stalling during transcript elongation
M Noe Gonzalez, D Blears, JQ Svejstrup - Nature reviews Molecular …, 2021 - nature.com
… for the maintenance of Pol II promoter-proximal pausing 53 , … interplay between
promoter-proximal pausing and pausing at … Advances in genome-wide Pol II mapping techniques …
promoter-proximal pausing and pausing at … Advances in genome-wide Pol II mapping techniques …
A role for FACT in RNA polymerase II promoter-proximal pausing
… ends of genes via Pol II that has been phosphorylated on Ser5 of its carboxy-terminal domain
(… through interaction with elongating Pol II phosphorylated on Ser2 of its CTD by the pause-…
(… through interaction with elongating Pol II phosphorylated on Ser2 of its CTD by the pause-…
RNA polymerase II dynamics shape enhancer–promoter interactions
… Notably, promoter-proximal paused Pol II itself partially … We extended our work genome-wide
using data from a CRISPRi … report that Pol II contributes to enhancer–promoter interaction …
using data from a CRISPRi … report that Pol II contributes to enhancer–promoter interaction …
Promoter-proximal regulation of gene transcription: key factors involved and emerging role of general transcription factors in assisting productive elongation
S Pal, D Biswas - Gene, 2023 - Elsevier
… regulation, promoter-proximal pausing of Pol II and its well-… a genome-wide stalling of Pol
II at the promoter-proximal sites … showed its interaction with DSIF and Pol II, however, it did …
II at the promoter-proximal sites … showed its interaction with DSIF and Pol II, however, it did …
RNA polymerase II pausing in development: orchestrating transcription
A Abuhashem, V Garg… - Open Biology, 2022 - royalsocietypublishing.org
… RNA polymerase II promoter-proximal pausing (Pol II pausing… of transcriptionally engaged
Pol II genome-wide at single base … Pol II pausing via a direct or indirect interaction with the …
Pol II genome-wide at single base … Pol II pausing via a direct or indirect interaction with the …