[HTML][HTML] Osteoarthritis year in review: genetics, genomics, epigenetics
… Main Upset plot shows number of publications (≥3) with … This year saw a dearth of large
genome-wide association … an increased risk of osteoporosis and lower bone mineral density (…
genome-wide association … an increased risk of osteoporosis and lower bone mineral density (…
[HTML][HTML] Osteoarthritis year in review 2022: Genetics, genomics and epigenetics
M Kim, A Rubab, WCW Chan, D Chan - Osteoarthritis and Cartilage, 2023 - Elsevier
… This is in concordance with the genome wide association … relationship between OA and
osteoporosis that is complex … showed that Lrrc15 is differentially methylated and expressed in OA …
osteoporosis that is complex … showed that Lrrc15 is differentially methylated and expressed in OA …
Assessment of DNA methylation patterns in the bone and cartilage of a nonhuman primate model of osteoarthritis
G Housman, LM Havill, EE Quillen, AG Comuzzie… - Cartilage, 2019 - journals.sagepub.com
… sites that were significantly differentially methylated across … be used to measure genome-wide
DNA methylation in baboon … specifically assess DNA methylation in skeletal tissues from …
DNA methylation in baboon … specifically assess DNA methylation in skeletal tissues from …
GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
U Styrkarsdottir, OA Stefansson, K Gunnarsdottir… - Nature …, 2019 - nature.com
… genome wide significant loci for DXA bone area. We also investigate association of these
variants with other bone related traits and diseases (BMD, height, osteoarthritis… of osteoporosis …
variants with other bone related traits and diseases (BMD, height, osteoarthritis… of osteoporosis …
DNA methylation of noncoding RNAs: new insights into osteogenesis and common bone diseases
… genome-wide DNA methylation to study the development of knee osteoarthritis; identified
DNA methylation … The degree of DNA methylation in the differentially methylated regions …
DNA methylation … The degree of DNA methylation in the differentially methylated regions …
DNA methylation and noncoding RNA in OA: Recent findings and methodological advances
V Izda, J Martin, C Sturdy, MA Jeffries - Osteoarthritis and cartilage open, 2021 - Elsevier
… in OA cartilage (Overview of differentially methylated pathways from studies included in …
genome-wide DNA methylation patterns in right distal femoral cartilage and subchondral bone of …
genome-wide DNA methylation patterns in right distal femoral cartilage and subchondral bone of …
Identification of Key Osteoporosis Genes Through Comparative Analysis of Men's and Women's Osteoblast Transcriptomes
D Chen, Y Li, Q Wang, P Zhan - Calcified Tissue International, 2023 - Springer
… -related diseases, including osteoporosis and osteoarthritis. … collection of all human
genome-wide association studies, and … methylation data and identified 451 differentially …
genome-wide association studies, and … methylation data and identified 451 differentially …
[HTML][HTML] Insights into the molecular landscape of osteoarthritis in human tissues
… with osteoarthritis, large-scale genome-wide association … This study compared subchondral
bone underlying low-… heart disease and cluster C with osteoporosis [43] . Replication of the …
bone underlying low-… heart disease and cluster C with osteoporosis [43] . Replication of the …
Identification of DNA methylation associated enrichment pathways in adults with non-specific chronic low back pain
… arthritis and osteoarthritis. Besides … against differential methylation being just a consequence
of co-morbidities. Second, the sample size of our study is relatively small for genome-wide …
of co-morbidities. Second, the sample size of our study is relatively small for genome-wide …
Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation–can blood be used as a surrogate for bone?
P Ebrahimi, H Luthman, FE McGuigan, KE Akesson - Epigenetics, 2021 - Taylor & Francis
… of bone traits has advanced thanks in part to genome-wide … (SNPs) associated with
osteoarthritis, and over 2000 … Sites which were differentially methylated in bone and blood (…
osteoarthritis, and over 2000 … Sites which were differentially methylated in bone and blood (…