[HTML][HTML] Osteoarthritis year in review: genetics, genomics, epigenetics

DA Young, MJ Barter, J Soul - Osteoarthritis and Cartilage, 2022 - Elsevier
… Main Upset plot shows number of publications (≥3) with … This year saw a dearth of large
genome-wide association … an increased risk of osteoporosis and lower bone mineral density (…

[HTML][HTML] Osteoarthritis year in review 2022: Genetics, genomics and epigenetics

M Kim, A Rubab, WCW Chan, D Chan - Osteoarthritis and Cartilage, 2023 - Elsevier
… This is in concordance with the genome wide association … relationship between OA and
osteoporosis that is complex … showed that Lrrc15 is differentially methylated and expressed in OA …

Assessment of DNA methylation patterns in the bone and cartilage of a nonhuman primate model of osteoarthritis

G Housman, LM Havill, EE Quillen, AG Comuzzie… - Cartilage, 2019 - journals.sagepub.com
… sites that were significantly differentially methylated across … be used to measure genome-wide
DNA methylation in baboon … specifically assess DNA methylation in skeletal tissues from …

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

U Styrkarsdottir, OA Stefansson, K Gunnarsdottir… - Nature …, 2019 - nature.com
genome wide significant loci for DXA bone area. We also investigate association of these
variants with other bone related traits and diseases (BMD, height, osteoarthritis… of osteoporosis

DNA methylation of noncoding RNAs: new insights into osteogenesis and common bone diseases

L Yu, K Xia, X Cen, X Huang, W Sun, Z Zhao… - Stem Cell Research & …, 2020 - Springer
genome-wide DNA methylation to study the development of knee osteoarthritis; identified
DNA methylation … The degree of DNA methylation in the differentially methylated regions

DNA methylation and noncoding RNA in OA: Recent findings and methodological advances

V Izda, J Martin, C Sturdy, MA Jeffries - Osteoarthritis and cartilage open, 2021 - Elsevier
… in OA cartilage (Overview of differentially methylated pathways from studies included in …
genome-wide DNA methylation patterns in right distal femoral cartilage and subchondral bone of …

Identification of Key Osteoporosis Genes Through Comparative Analysis of Men's and Women's Osteoblast Transcriptomes

D Chen, Y Li, Q Wang, P Zhan - Calcified Tissue International, 2023 - Springer
… -related diseases, including osteoporosis and osteoarthritis. … collection of all human
genome-wide association studies, and … methylation data and identified 451 differentially

[HTML][HTML] Insights into the molecular landscape of osteoarthritis in human tissues

G Katsoula, P Kreitmaier, E Zeggini - Current Opinion in …, 2022 - journals.lww.com
… with osteoarthritis, large-scale genome-wide association … This study compared subchondral
bone underlying low-… heart disease and cluster C with osteoporosis [43] . Replication of the …

Identification of DNA methylation associated enrichment pathways in adults with non-specific chronic low back pain

EN Aroke, DS Overstreet, TM Penn… - Molecular …, 2020 - journals.sagepub.com
… arthritis and osteoarthritis. Besides … against differential methylation being just a consequence
of co-morbidities. Second, the sample size of our study is relatively small for genome-wide

Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation–can blood be used as a surrogate for bone?

P Ebrahimi, H Luthman, FE McGuigan, KE Akesson - Epigenetics, 2021 - Taylor & Francis
… of bone traits has advanced thanks in part to genome-wide … (SNPs) associated with
osteoarthritis, and over 2000 … Sites which were differentially methylated in bone and blood (…