[HTML][HTML] Epigenetic regulation of skeletal tissue integrity and osteoporosis development
YS Chen, WS Lian, CW Kuo, HJ Ke, SY Wang… - International Journal of …, 2020 - mdpi.com
… delays chondrocyte loss and cartilage erosion during osteoarthritis development [34]. While
… with genome-wide analyses revealed that rs11614913T in the MIR196A2 gene in bone …
… with genome-wide analyses revealed that rs11614913T in the MIR196A2 gene in bone …
Intra-and Inter-Specific Investigations of Skeletal DNA Methylation and Femur Morphology in Primates
… skeletal pathologies and disorders, such as osteoporosis … genome-wide and gene-specific
DNA methylation in primate … were significantly differentially methylated across comparative …
DNA methylation in primate … were significantly differentially methylated across comparative …
The crucial mechanism and therapeutic implication of RNA methylation in bone pathophysiology
C Yang, Z Dong, Z Ling, Y Chen - Ageing Research Reviews, 2022 - Elsevier
… bone diseases include a variety of diseases such as osteoporosis (OP), osteoarthritis (OA), …
The opposite function of IGF2BPs to YTHDF2 shows the core functions of reader proteins in …
The opposite function of IGF2BPs to YTHDF2 shows the core functions of reader proteins in …
Mapping 5-hydroxymethylcytosine (5hmC) modifications in skeletal tissues using high-throughput sequencing
FC Grandi, N Bhutani - Osteoporosis and Osteoarthritis, 2021 - Springer
… However, the challenge with profiling 5hmC is that it typically … can be used for downstream
genome-wide or targeted 5hmC … better indication of the fragment profile and concentration. A …
genome-wide or targeted 5hmC … better indication of the fragment profile and concentration. A …
[HTML][HTML] The regulation of bone metabolism and disorders by Wnt signaling
K Maeda, Y Kobayashi, M Koide, S Uehara… - International journal of …, 2019 - mdpi.com
… of Wnt signaling in osteoporosis, osteoarthritis, rheumatoid … Further, the long bone in OPG-KO
revealed a significant increase … A genome-wide association study (GWAS) has identified a …
revealed a significant increase … A genome-wide association study (GWAS) has identified a …
Nuclear mechanosensing controls MSC osteogenic potential through HDAC epigenetic remodeling
AR Killaars, CJ Walker… - Proceedings of the …, 2020 - National Acad Sciences
… Collectively, our results reveal that nuclear mechanosensing … bone-specific diseases, such
as osteoporosis, osteoarthritis, … cause osteoarthritis (42), and differentially methylated genes, …
as osteoporosis, osteoarthritis, … cause osteoarthritis (42), and differentially methylated genes, …
[HTML][HTML] Epigenetic modifications in spinal ligament aging
Q Xiang, Y Zhao, J Lin, S Jiang, W Li - Ageing Research Reviews, 2022 - Elsevier
… as osteoporosis and osteoarthritis (Marini et al., 2016). And increasing studies investigating
genome-wide or gene-specific methylation profiles … There were 550 differentially methylated …
genome-wide or gene-specific methylation profiles … There were 550 differentially methylated …
Postnatal Social Factors: The Epigenome and the Skeleton
A Santurtún, A del Real, JA Riancho - Bone Health: A Reflection of the …, 2019 - Springer
… Genome-wide analysis has shown that abuse is associated … of patients with osteoarthritis
and with osteoporosis, whereas … with osteoarthritis, we found several differentially methylated …
and with osteoporosis, whereas … with osteoarthritis, we found several differentially methylated …
[HTML][HTML] Long noncoding RNAs: a missing link in osteoporosis
AM Silva, SR Moura, JH Teixeira, MA Barbosa… - Bone research, 2019 - nature.com
… lncRNAs in osteoporosis only recently started to be revealed. … Whole transcriptome profiling
studies revealed that lncRNAs … altered in bone inflammatory conditions, as osteoarthritis and …
studies revealed that lncRNAs … altered in bone inflammatory conditions, as osteoarthritis and …
[HTML][HTML] Impact of environmental and epigenetic changes on mesenchymal stem cells during aging
N Smith, S Shirazi, D Cakouros, S Gronthos - International Journal of …, 2023 - mdpi.com
… skeletal diseases such as osteoporosis and osteoarthritis, … It was revealed that Bmncr
upregulates the extracellular … that DNA methylation was altered in a genome-wide manner in …
upregulates the extracellular … that DNA methylation was altered in a genome-wide manner in …