DNA methylation in Alzheimer's disease: In brain and peripheral blood

X Wei, L Zhang, Y Zeng - Mechanisms of Ageing and Development, 2020 - Elsevier
… found an increase in global DNA methylation in peripheral blood mononuclear cells which is
… and expression of APP by researching peripheral blood mononuclear cells in the AD when …

[HTML][HTML] Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer's disease

M Konki, M Malonzo, IK Karlsson, N Lindgren… - Clinical …, 2019 - Springer
… examined in individual peripheral blood mononuclear cells (PBMCs) … The proportions of
blood cell types expressing these genes … (Cell Ranger aggr tool) was normalized using a global-…

[HTML][HTML] Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

…, Alzheimer's Disease Neuroimaging Initiative (ADNI) - Clinical …, 2020 - Springer
… Nearly 44 million people worldwide have Alzheimers disease (AD) or a … to understand
patterns of peripheral blood DNA methylation in the ADNI … Peripheral blood mononuclear cells

… the RE-1 silencing transcription factor in peripheral blood mononuclear cells and gene expression of antioxidant enzyme in patients with late-onset Alzheimer disease

I González-Mundo, NM Pérez-Vielma… - Experimental …, 2020 - Elsevier
… Late-onset Alzheimer disease (LOAD) is the leading cause of dementia worldwide, affecting
… Herein we propose that DNA methylation of the REST1 promoter region may suppress the …

Integrative analysis of DNA methylation and gene expression identifies genes associated with biological aging in Alzheimer's disease

…, Alzheimer's Disease Neuroimaging … - Alzheimer's & …, 2022 - Wiley Online Library
… participants in the Alzheimer's Disease Neuroimaging Initiative (ADNI). First, we … DNA
methylation data to estimate DNA methylation–based epigenetic clocks 5, 6 and DNA methylation–…

[HTML][HTML] DNA methylation in neurodegenerative and cerebrovascular disorders

O Martínez-Iglesias, I Carrera, JC Carril… - International journal of …, 2020 - mdpi.com
methylation status of a transgenic Alzheimers disease … in late-onset AD in blood mononuclear
cells [28]. Once again, the … -coated tube from peripheral blood and after centrifugation the …

DNA methylation analysis of candidate genes associated with dementia in peripheral blood

PD Fransquet, P Lacaze, R Saffery, J Phung… - …, 2020 - Taylor & Francis
… Here, we measured DNA methylation changes across these six candidate genes in blood
… itself, as has been seen previously in Alzheimers disease [Citation56]. Should an easy to …

[HTML][HTML] Distinct CSF biomarker-associated DNA methylation in Alzheimer's disease and cognitively normal subjects

W Zhang, JI Young, L Gomez, MA Schmidt… - Alzheimer's research & …, 2023 - Springer
… to identify blood DNA methylation associated with CSF biomarkers in the Alzheimers
Disease … of the regulatory changes associated with different pathological disease-associated …

[HTML][HTML] Attempt to predict A/T/N-based Alzheimer's disease cerebrospinal fluid biomarkers using a peripheral blood DNA methylation clock

…, Alzheimer's Disease Neuroimaging … - … Alzheimer's disease …, 2020 - content.iospress.com
… Note: [1] Data used in preparation of this article were obtained from the Alzheimers Disease
Neuroimaging Initiative (ADNI) database (http://adni.loni.usc.edu). As such, the investigators …

[HTML][HTML] Alzheimer's disease-associated (hydroxy) methylomic changes in the brain and blood

…, A Kawalia, P Hoffmann, T Luck, S Riedel-Heller… - Clinical …, 2019 - Springer
… [17], and differences in global levels of DNA methylation and … In addition, we explored DNA
methylation in blood samples … OXT hypermethylation in the DNA from peripheral blood of …