Chronic high fat diet impairs glucagon like peptide-1 sensitivity in vagal afferents

A Al Helaili, SJ Park, MJ Beyak - Biochemical and Biophysical Research …, 2020 - Elsevier
… afferents in mediating the anorexigenic effects of glucagon-like peptide-1 (… -1 inhibited
voltage-gated K + channels, resulting in vagal afferent excitation [28]. This ion channel mechanism

Endocannabinoid regulation of gastric vagal afferent signalling

SD Christie - 2020 - digital.library.adelaide.edu.au
afferent mediated manners. In the small intestines, glucagon-like peptide 1 (GLP-1), peptide
tyrosine tyrosine (… CCK acts via vagal afferent neurones to inhibit gastrointestinal motility and …

[HTML][HTML] GLP-1 attenuates intestinal fat absorption and chylomicron production via vagal afferent nerves originating in the portal vein

S Hoffman, D Alvares, K Adeli - Molecular Metabolism, 2022 - Elsevier
… One such peptide, glucagon-like peptide (GLP)-1 has been … well-documented effect on
gastric emptying we then sought to … the portal vein stimulates GLP-1R on vagal afferent neurons, …

Endogenous glucagonlike peptide (GLP)‐1 as alternative for GLP‐1 receptor agonists: Could this work and how?

MM Smits, JJ Holst - Diabetes/metabolism research and …, 2023 - Wiley Online Library
… intravenous glucagonlike peptide1 on gastric emptying and … are potent inhibitors of vagally
induced gastric acid secretion … size in the rat via different mechanisms. Endocrinology. 2009;…

The locus coeruleus contributes to the anorectic, nausea, and autonomic physiological effects of glucagon-like peptide-1

SM Fortin, JC Chen, MC Petticord, FJ Ragozzino… - Science …, 2023 - science.org
… Administration–approved glucagon-like peptide-1 receptor (GLP-… Given the reduction in
gastric emptying by LC Ex-4, we next … We observed that LC Ex-4 stimulates kaolin intake in rats, …

Effects of GLP-1 and its analogs on gastric physiology in diabetes mellitus and obesity

DB Maselli, M Camilleri - Diabetes: from Research to Clinical Practice …, 2021 - Springer
… of vagal mechanisms in the delay of gastric emptying induced … central component, there is
evidence that GLP-1 inhibits … levels of glucagon-like peptide-1 on appetite, gastric emptying, …

Microbiota-gut-brain axis: Relationships among the vagus nerve, gut microbiota, obesity, and diabetes

S Longo, S Rizza, M Federici - Acta diabetologica, 2023 - Springer
… roles of the vagus nerve and glucagon like peptide-1 in appetite … endocannabinoid production
stimulates afferent sensory … pyloric sphincter and slowing gastric emptying. GIP promotes …

Gastrointestinal vagal afferents and food intake: relevance of circadian rhythms

AJ Page - Nutrients, 2021 - mdpi.com
… release of the gut hormones glucagon-like peptide 1 (GLP-1) … regulation of gut motility (eg,
gastric emptying) and intestinal … In this study it was observed that the spinal afferent mediated

Estrogen and gut satiety hormones in vagus-hindbrain axis

KP Huang, HE Raybould - Peptides, 2020 - Elsevier
… as cholecystokinin, glucagon-like peptide 1 and leptin are … inhibition of gastric acid secretion
and delay of gastric emptying [… input from vagal afferent-mediated anorexigenic signals [81]. …

Serotonergic Modulation of the Central GLP-1 System

RML Huamancaja - 2021 - search.proquest.com
… (5-HT) and the central glucagon-like peptide-1 (GLP-1) system, … ” and “slow” mechanisms
that drive our biological response … periphery via glutamatergic signaling from the vagus nerve (…