Brain trauma, glucocorticoids and neuroinflammation: dangerous liaisons for the hippocampus
IG Komoltsev, NV Gulyaeva - Biomedicines, 2022 - mdpi.com
… in the level of excitatory amino acids in the extracellular space [49]. … MCAO induces
accumulation of the pro-inflammatory … induced by intra-amygdaloid injections of kainic acid. Eur. J. …
accumulation of the pro-inflammatory … induced by intra-amygdaloid injections of kainic acid. Eur. J. …
Insights into the therapeutic potential of glucocorticoid receptor modulators for neurodegenerative diseases
AF De Nicola, M Meyer, R Guennoun… - International journal of …, 2020 - mdpi.com
… of the behavioral, inflammatory, excitatory, and cell-death-… in the hippocampus in the kainic
acid model of excitotoxicity [53]. … 25–35 peptide accumulation disappeared after treatment …
acid model of excitotoxicity [53]. … 25–35 peptide accumulation disappeared after treatment …
Neuroinflammation and neuronal loss in the hippocampus are associated with immediate posttraumatic seizures and corticosterone elevation in rats
IG Komoltsev, SO Frankevich, NI Shirobokova… - International Journal of …, 2021 - mdpi.com
… K+, a decrease in Ca2+, changes in pH, accumulation of … excitatory neurotransmission [7].
Effects of GCs on neuronal excitability mediated by mineralocorticoid and glucocorticoid …
Effects of GCs on neuronal excitability mediated by mineralocorticoid and glucocorticoid …
Excitatory amino acid transporters in physiology and disorders of the central nervous system
AR Malik, TE Willnow - International journal of molecular sciences, 2019 - mdpi.com
… toxic accumulation of this amino acid in the extracellular space. In … of EAATs levels are
glucocorticoids which increase EAAT2 … of EAAT3 decreased after kainic acid stimulation [132,133] …
glucocorticoids which increase EAAT2 … of EAAT3 decreased after kainic acid stimulation [132,133] …
Levetiracetam ameliorated amyloidosis and tauopathy in mice with dexamethasone-induced Alzheimer's disease
X Zheng, HC Zhang, ZW Wei, YD Lv, FY Jin, J Zhu… - 2023 - researchsquare.com
… detrimental impact of chronic glucocorticoid exposure on AD … Extracellular accumulation of
Aβ in SPs in brains with AD is a … neurons via apoptosis inhibition in kainic acid (KA)-activated …
Aβ in SPs in brains with AD is a … neurons via apoptosis inhibition in kainic acid (KA)-activated …
Glutamate-Mediated Excitotoxicity in the Pathogenesis and Treatment of Neurodevelopmental and Adult Mental Disorders
… may result in the accumulation of excessive glutamate levels, … the extracellular space by
neuronal and astrocytic excitatory … the levels of the stress hormone glucocorticoid, which, in turn, …
neuronal and astrocytic excitatory … the levels of the stress hormone glucocorticoid, which, in turn, …
Emerging evidence for the widespread role of glutamatergic dysfunction in neuropsychiatric diseases
T McGrath, R Baskerville, M Rogero, L Castell - Nutrients, 2022 - mdpi.com
… , potentially leading to a gradual accumulation of brain glutamine/… HPA glucocorticoids
provide feedback to the CNS and activate … This results in a widespread surge of excitatory …
provide feedback to the CNS and activate … This results in a widespread surge of excitatory …
Pathophysiological Cascade of Events Leading to Epilepsy: Role of Inflammation
FO Kamel, HSAEK Eweis… - Journal of …, 2021 - research.manuscritpub.com
… depolarization caused by a giant synaptic excitatory … induction [42,43]. In addition to
the hippocampus and cerebral cortex in kainic acid (KA) as well as electroconvulsive shockinduced …
the hippocampus and cerebral cortex in kainic acid (KA) as well as electroconvulsive shockinduced …
Rufinamide (RUF) suppresses inflammation and maintains the integrity of the blood–brain barrier during kainic acid-induced brain damage
H Yu, B He, X Han, T Yan - Open Life Sciences, 2021 - degruyter.com
… Kainic acid (KA) is a glutamic acid analogue of excitatory toxicity, which can be used to simulate
excitatory toxicity caused … in young rats, accompanied by accumulation of microglia [28]. …
excitatory toxicity caused … in young rats, accompanied by accumulation of microglia [28]. …
Intracellular signaling cascades in bipolar disorder
… Glutamate is the most abundant excitatory neurotransmitter in the brain. It acts in three …
(MR) intracellular receptors. The human stress response increases glucocorticoid secretion, …
(MR) intracellular receptors. The human stress response increases glucocorticoid secretion, …