[HTML][HTML] Ionotropic glutamate receptors in epilepsy: a review focusing on AMPA and NMDA receptors

T Hanada - Biomolecules, 2020 - mdpi.com
… completely blocked seizures when rats were stimulated with a … an enhanced response to
glutamate in the epileptic brain due to … Similar pre-ictal discharge was observed in brain slice

[HTML][HTML] Deep brain stimulation restores the glutamatergic and GABAergic synaptic transmission and plasticity to normal levels in kindled rats

S Ghafouri, Y Fathollahi, S Semnanian, A Shojaei… - PLoS …, 2019 - journals.plos.org
… synapses in hippocampal slices of kindled rats. When … transmission in generation of
epileptic discharges [52, 53]. However, there are different reports about GABAergic system activity

[HTML][HTML] … of the Effects of Pentose Phosphate Pathway Inhibition on the Generation of Reactive Oxygen Species and Epileptiform Activity in Hippocampal Slices

D Ponomareva, A Ivanov, P Bregestovski - International Journal of …, 2024 - mdpi.com
… inhibition of the GABA A receptors [40] or an increase in spontaneous glutamate release [41]…
, it is expected that NADPH may contribute to the total autofluorescence signal. Changes in …

Pannexin-1 channels in epilepsy

MS Aquilino, P Whyte-Fagundes, G Zoidl… - Neuroscience Letters, 2019 - Elsevier
contributes to the dynamics observed during epileptic activity… P2X purinergic receptors to
release glutamate and provide … Of interest, adenosine production in hippocampal slices was …

[HTML][HTML] Bidirectional dysregulation of AMPA receptor-mediated synaptic transmission and plasticity in brain disorders

H Zhang, CR Bramham - Frontiers in Synaptic Neuroscience, 2020 - frontiersin.org
… AMPA receptors (AMPARs) are glutamate-gated ion channels … extrasynaptic compartments
via lateral diffusion and are reversibly … in male but not female rats. Maternally separated male …

… of ancient retrovirus, forms virus-like particles, which are abundantly generated by neurons during epileptic seizures, and affects epileptic susceptibility in rodent …

DA Sibarov, V Tsytsarev, A Volnova… - Frontiers in …, 2023 - frontiersin.org
… It is known that the epileptic activity of neurons depends on … Activation of calcium entry via
ionotropic glutamate receptors, … were studied, except 17 neocortical temporal lobe samples in …

Neurobiology, functions, and relevance of excitatory amino acid transporters (EAATs) to treatment of refractory epilepsy

AV Zaitsev, IV Smolensky, P Jorratt, SV Ovsepian - CNS drugs, 2020 - Springer
… related to glutamatergic hyperactivity and glutamate-induced … , was shown in transplants
with epileptiform activity [87]. … In the neocortex, astrocytic processes are associated with only …

[HTML][HTML] What is the Role of Lithium in Epilepsy?

SL Bojja, N Singh, KK Kolathur… - Current …, 2022 - ncbi.nlm.nih.gov
slice cultures, pilocarpine treatment produced epileptiform … in the brain that can cause
epileptic discharge. In the in vitro … glutamate-induced excitotoxicity in rat cortical neurons [102]. …

[HTML][HTML] Brain temperature alters contributions of excitatory and inhibitory inputs to evoked field potentials in the rat frontal cortex

M Gotoh, K Nagasaka, M Nakata… - Frontiers in Cellular …, 2020 - frontiersin.org
… Twelve rats were used in Experiment 6. We examined the effects of glutamate on the evoked
… in Experiment 5–7) were embedded in paraffin and sliced into coronal sections of 8 μm …

[HTML][HTML] Connexins-based hemichannels/channels and their relationship with inflammation, seizures and epilepsy

L Medina-Ceja, JC Salazar-Sánchez… - International Journal of …, 2019 - mdpi.com
… of glutamate [111], and the overactivation of their receptors in … support epileptic activity by
supplying glucose to epileptic … : Neocortical slices Neocortical slices from epileptic patients (…