Insulin and growth hormone balance: implications for obesity

Z Huang, L Huang, MJ Waters, C Chen - Trends in Endocrinology & …, 2020 - cell.com
… reduced levels of growth hormone, GH) often occurs in pre‐obesity and obesity. Using distinct
… Use of the [insulin]:[GH] ratio as a biomarker for predicting the development of obesity is …

Growth hormone receptor deficiency in humans associates to obesity, increased body fat percentage, a healthy brain and a coordinated insulin sensitivity

J Guevara-Aguirre, E Teran, D Lescano… - Growth Hormone & IGF …, 2020 - Elsevier
… We have shown that subjects with Laron syndrome (LS) due to growth hormone receptor …
absent growth hormone receptor and the diminished concentrations of the insulin-like growth

The effects of growth hormone on adipose tissue: old observations, new mechanisms

JJ Kopchick, DE Berryman, V Puri, KY Lee… - Nature Reviews …, 2020 - nature.com
Obesity is associated with excess morbidity and mortality … of obesity and are controlled by
afferent signals including a variety of hormones, for example, catecholamines, growth hormone

[HTML][HTML] Effect of growth hormone therapy on liver enzyme and other cardiometabolic risk factors in boys with obesity and nonalcoholic fatty liver disease

J Xue, S Liang, J Ma, Y Xiao - BMC Endocrine Disorders, 2022 - Springer
… and growth hormone (GH)-insulin-like growth factor 1(IGF-1) axis, no study further investigates
whether or not recombinant human GH (rhGH) treatment can improve NAFLD in obese

[HTML][HTML] Growth hormone and aging: new findings

A Bartke, E Hascup, K Hascup… - The World Journal of …, 2021 - ncbi.nlm.nih.gov
… January 2019, we presented the evidence that growth hormone (GH) has an important role
… weight, and obese individuals. Similar association of increased obesity and increased levels …

Growth hormone deficiency: health and longevity

MH Aguiar-Oliveira, A Bartke - Endocrine reviews, 2019 - academic.oup.com
… Individuals with IGHD are characterized by proportional short stature, doll facies, high-pitched
voices, and central obesity. They have delayed puberty but are fertile and generally …

[HTML][HTML] Obesity: The Relationship between Growth Hormone and Exercises

DC de Sá-Caputo, M Bernardo-Filho… - Growth Hormone …, 2023 - intechopen.com
… management of obesity. The aim of this chapter is to integrate knowledge about the relevance
of exercises and/or growth hormone (GH) to the management of individuals with obesity. …

Growth hormone and counterregulation in the pathogenesis of diabetes

X Dong, L Su, ME Patti - Current diabetes reports, 2022 - Springer
… [89, 94, 95]; higher levels of free (bioavailable) IGF-1 may contribute to the normal growth
in children with obesity despite markedly impaired GH secretion. On the other hand, other …

[HTML][HTML] Physiology, obesity neurohormonal appetite and satiety control

AY Yeung, P Tadi - 2020 - europepmc.org
… From knowing that ghrelin was a growth hormone and leptin's effects in regulating body …
[9] The primary receptor of ghrelin is the growth hormone secretagogue receptor type 1a (GHS-…

[HTML][HTML] Obesity and its impact on COVID-19

AJM de Leeuw, MAM Oude Luttikhuis… - Journal of Molecular …, 2021 - Springer
obesity emerged as one of the major risk factors for developing severe COVID-19. Here we
review the biology of coronavirus infections in relation to obesity… , leptin, and growth hormone