Nuclear export of mRNAs with disease pathogenesis and therapeutic implications

S Guha, P Barman, A Manawa, SR Bhaumik - Messenger RNA …, 2022 - Springer
co-transcriptionally, unlike NXF1-mediated mRNA export. CRM1 requires Ran-GTP for
high-affinity binding to … Another disorder caused by pre-mRNA mutation is the myotonic dystrophy …

Nuclear mRNA maturation and mRNA export control: from trypanosomes to opisthokonts

S Kramer - Parasitology, 2021 - cambridge.org
… maturation steps occur co-transcriptionally. During maturation, the pre-mRNA interacts with
… For example, the CBC binds to the Yra1/ALYREF subunit of the TREX complex and recruits …

Nuclear export of plant pararetrovirus mRNAs involves the TREX complex, two viral proteins and the highly structured 5′ leader region

J Kubina, A Geldreich, JP Gales… - Nucleic Acids …, 2021 - academic.oup.com
… subcomplex, act as a binding platform for the export receptor … /p15: histone mRNAs bind
SR adaptor proteins that directly … nucleus, interact with UAP56, and bind to single and double-…