… adult T cell leukemia/lymphoma (ATL) decades after infection… the mechanisms of action of
Tax and HBZ with the comprehensive … activities of Tax and Rex, HTLV-1 structural proteins are …

… ) causes an array of pathologies, the most aggressive of which is adult T-cell leukemia (ATL),
a … and on the interplay between these two viral proteins (Tax and HBZ) with the host innate …

… caused by the virus: adult T cell leukemia/lymphoma (ATL) (3… to Tax and HBZ, respectively,
in limiting the HTLV-1 proviral … lysis of HTLV-1 infected cells is limited by weak HBZ protein …

… ) and helix basic zipper protein (HBZ), which are considered … HTLV-1 are largely attributed
to the effects of the Tax protein. … alterations that result in adult T-cell leukemia lymphoma. …

… ) is the etiological agent of adult T-cell leukemia/lymphoma (… The HTLV-1 trans-activator
protein Tax is expressed from a … In addition to Tax, HBZ is a key viral factor important for HTLV-1 …

… is the causative agent of a spectrum of diseases including the aggressive adult T-cell … -HTLV-1-targeted
therapies of ATL with a special focus on two viral proteins, Tax and HBZ, …

… The viral protein Tax-1, together with additional regulatory proteins, in particular … agent is
HTLV-1, which causes adult T-cell leukemia/lymphoma (ATLL), a malignancy of mature CD4+ T-…

… While Tax-1 can be found in both the cytoplasm and nucleus of … of HTLV-1 HBZ protein
during adult T-cell leukemia-lymphoma progression. Primary infection of T cells by HTLV-1 is …

… ) is the etiological agent of adult T-cell leukemia/lymphoma (… HTLV-1 HBZ protein allows
HeLa cells to express Tax stably, albeit at a low level. Furthermore, although HTLV-1 infection in …

… of HBZ on Tax-induced transformation and cellular effects. This study helps understanding
long-term HTLV-1 … Adult T-cell Leukemia/Lymphoma (ATL) is an aggressive hematological …