Insights on metabolic reprogramming and its therapeutic potential in acute leukemia

L Di Martino, V Tosello, E Peroni, E Piovan - International Journal of …, 2021 - mdpi.com
… could represent good candidates for the development of … by the intervention of ATP-binding
cassette proteins (ABCC1-4 … significant regression of engrafted mouse lymphomas [100,101]. …

Increased/Targeted Brain (Pro) Drug Delivery via Utilization of Solute Carriers (SLCs)

J Huttunen, SK Adla, M Markowicz-Piasecka… - Pharmaceutics, 2022 - mdpi.com
… via numerous ATP-binding cassette (ABC) transporters, including … (a liver disease where the
flow of bile from the liver is … efflux transport direction makes them less suitable candidates for …

[HTML][HTML] Exploring Host Factors of the Human Metabolism as Promising Targets for Dengue Treatment

NC Tavares, CS Nascimento, JG de Oliveira… - 2024 - intechopen.com
… DENV entry, such as dendritic cell-specific intercellular adhesion molecule-3-… lipid
homeostasis. ApoAI interacts with membrane lipid transporters, including those of the ATP-binding

[HTML][HTML] Extracellular vesicles: A novel tool facilitating personalized medicine and pharmacogenomics in oncology

K Goričar, V Dolžan, M Lenassi - Frontiers in pharmacology, 2021 - frontiersin.org
putative EV-bound protein and RNA biomarkers were … (UGT) and ATP-binding cassette
(ABC) transporters. CYPs and … ABC transporter ABCB1, also known as multidrug resistance …

Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases

AN Saiyed, AR Vasavada, SRK Johar - Future Journal of Pharmaceutical …, 2022 - Springer
transporters such as ATP binding cassette (ABC) and solute … 122 strand significantly regulate
liver disease mechanisms and … was shown to be effective for both systemic and cell-specific

Lesion-remote astrocytes govern microglia-mediated white matter repair

S McCallum, KB Suresh, T Islam, AW Saustad… - bioRxiv, 2024 - biorxiv.org
ATP-binding cassette (ABC) transporters, ABCA1 and ABCG1. … macrophage inflammatory
profile via a common liver X receptor α… Cell-specific and region-specific transcriptomics in the …

Role of Tissue Inhibitor of Metalloproteinase 4 (TIMP4) and TIMP3 in Vascular Diseases

M Hu - 2023 - era.library.ualberta.ca
… the thoracic aorta) compared to Ldlr-/- mice. Although plasma lipid and cholesterol levels
were lower in Ldlr-/-/Timp4-/--HFD mice, cholesterol content in the abdominal aorta was higher …

[PDF][PDF] Investigation into the oncogenic role of BRUNOL5 and the role of BRUNOL5 in the anti-cancer effects of dietary polyphenols in primary liver cancer cells

TJH Yang - 2023 - open.library.ubc.ca
… We then investigated various candidate upregulated transcripts, … Our findings indicate that
BRUNOL5 is a novel … to decrease global m6A RNA levels in the liver of mice fed a high-fat diet …

Hematopoietic progenitors and the bone marrow niche shape the inflammatory response and contribute to chronic disease

Y Xu, AJ Murphy, AJ Fleetwood - International Journal of Molecular …, 2022 - mdpi.com
… in diabetic mice with sodium glucose co-transporter 2 inhibitor (… that include the ATP-binding
cassette (ABC) transporters, which … This type of approach enables cell-specific targeting in a …

Ovarian cancer stem cells: role in metastasis and opportunity for therapeutic targeting

X Zong, KP Nephew - Cancers, 2019 - mdpi.com
… hilum of the OSE in mice, characterized by cells expressing … of Wnt/β-catenin-ATP-binding
cassette G2 signaling in OC cell lines … distant metastatic location is the liver, followed by distant …