Retinoid metabolism and functions mediated by retinoid binding-proteins
… retinoids in the aqueous cellular medium, and allow retinoid … In extra-hepatic tissues, Crbp1
sequesters retinol transferred into … Isolation of retinoids from the cellular milieu within Crbp1 (…
sequesters retinol transferred into … Isolation of retinoids from the cellular milieu within Crbp1 (…
[HTML][HTML] Retinoid homeostasis and beyond: how retinol binding protein 4 contributes to health and disease
JS Steinhoff, A Lass, M Schupp - Nutrients, 2022 - mdpi.com
… distribute hepatic vitamin A stores to extrahepatic tissues. In particular, binding of RBP4 to
‘stimulated by retinoic … crystal structure of human retinol-free RBP4 isolated from serum, urine, …
‘stimulated by retinoic … crystal structure of human retinol-free RBP4 isolated from serum, urine, …
Biochemistry and pharmacology of retinoids
WS Blaner - Retinoids in oncology, 2020 - taylorfrancis.com
… Specific binding proteins for both retinol and retinoic acid have … in hepatic retinoid metabolism,
the question of how retinoid … and binding proteins in isolated rat liver cells. J Biol Chem …
the question of how retinoid … and binding proteins in isolated rat liver cells. J Biol Chem …
[HTML][HTML] Impaired hepatic vitamin A metabolism in NAFLD mice leading to vitamin A accumulation in hepatocytes
A Saeed, P Bartuzi, J Heegsma, D Dekker… - Cellular and molecular …, 2021 - Elsevier
… Hepatic retinol and retinol binding protein 4 (RBP4) levels were … (C) Freshly isolated and
4-hour attached primary rat … hepatic levels of the various retinoids (retinyl esters, retinol …
4-hour attached primary rat … hepatic levels of the various retinoids (retinyl esters, retinol …
The molecular aspects of absorption and metabolism of carotenoids and retinoids in vertebrates
MAK Widjaja-Adhi, M Golczak - … et Biophysica Acta (BBA)-Molecular and …, 2020 - Elsevier
… numerous specialized retinoid-transport proteins, receptors, and enzymes. … hepatic pool of
retinoids requires the hydrolysis of REs, transport of ROL back to the hepatocytes, and binding …
retinoids requires the hydrolysis of REs, transport of ROL back to the hepatocytes, and binding …
Retinol-binding protein 2 (RBP2): biology and pathobiology
WS Blaner, PJ Brun, RM Calderon… - Critical reviews in …, 2020 - Taylor & Francis
… than retinol, retinaldehyde, or retinoic acid (see Ligand binding … The increase in hepatic
Rbp2 expression upon pregnancy was … Studies of isolated DCs have identified that granulocyte-…
Rbp2 expression upon pregnancy was … Studies of isolated DCs have identified that granulocyte-…
[HTML][HTML] Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes
AV Klyuyeva, OV Belyaeva, KR Goggans… - Journal of Biological …, 2021 - ASBMB
… The bioactive derivative of vitamin A, retinoic acid (RA), was … the dynamics of hepatic retinoid
metabolism and signaling in … qPCR analysis was performed using mRNA isolated from the …
metabolism and signaling in … qPCR analysis was performed using mRNA isolated from the …
[HTML][HTML] Retinol-binding protein-4 and nonalcoholic fatty liver disease
H Huang, C Xu - Chinese Medical Journal, 2022 - journals.lww.com
… [8] Since its first isolation from the human serum in 1968, … Stimulated-by-retinoic acid-6
(STRA6) is the specific receptor … to the related metabolic enzymes. [18] STRA6 is expressed in the …
(STRA6) is the specific receptor … to the related metabolic enzymes. [18] STRA6 is expressed in the …
[HTML][HTML] The role of the retinoid receptor, RAR/RXR heterodimer, in liver physiology
B Li, SY Cai, JL Boyer - Biochimica et Biophysica Acta (BBA)-Molecular …, 2021 - Elsevier
… ) is the rate-limiting enzyme in bile acid synthesis. The … in freshly isolated rat HSC where
treatment with retinoids decreased … relate to hepatic lipid metabolism, bile acid metabolism and …
treatment with retinoids decreased … relate to hepatic lipid metabolism, bile acid metabolism and …
[HTML][HTML] … correlated with total liver retinol concentrations in male Mongolian gerbils, but only partially explained by chylomicron deposition assessed with total α-retinol
J Sheftel, M Sowa, L Mourao, LT Zoué, CR Davis… - Current developments in …, 2019 - Elsevier
… through the binding of the oxidation product retinoic acid to … α-retinol metabolism quantitatively
trace retinol metabolism (… to RBP4 delivery of retinol (but not α-retinol, which cannot bind …
trace retinol metabolism (… to RBP4 delivery of retinol (but not α-retinol, which cannot bind …