… connective tissue constitutes a large portion of the human body and pathological changes
may affect many organs. Hereditary connective tissue disorders … of the connective tissue (Van …

Background Heritable disorders of connective tissue (HDCT) is a heterogeneous group of
conditions caused by defects in genes responsible for extracellular matrix elements. Although …

… One would argue hEDS is another all-encompassing classification for heritable connective
tissue disorders and or acquired musculoskeletal conditions without a definitive molecular …

A connective tissue disorder is any disease that impacts the structures between cells,
typically impacting collagen or elastin protein production or function. Heritable disorders of …

… Defining the disease phenotypes for these rare disorders is a continuing challenge. Because
connective tissue is ubiquitous in the human body, the hereditary HDCT affect multiple …

… connective tissue disorders, the European Reference Network (ERN) Skin-Mendelian connective
tissue disorders … children and adolescents with (heritable) connective tissue disorders”. …

… We analyzed 199 individuals with hereditary aortopathy or related connective tissue
disorder. The majority of patients had vascular complications such as TAAD, carotid artery …

… disorders are characterized by accelerated signs and symptoms of ageing. Other hereditary
… of genes encoding for components of connective tissue and are less common than diseases …

… Though soft tissue disorders have been recognized and described to some detail in several
… Hereditary equine regional dermal asthenia (HERDA), or hyperelastosis cutis, has been …

… This review addresses the involvement of oxidative stress in the pathogenesis and progression
of connective tissue genetic diseases, of which most of them belong to the large family of …