… important role in predicting the pathogenesis of CLL patients. … Overexpression of ZAP-70
(>20%) in CLL patients can be … the hypothesis that the expression level of CD markers in cells …

… maintenance therapy with anti-CD20 monoclonal antibodies or lenalidomide) … 20 As such,
one or even several biomarkers are not sufficiently robust to accurately and precisely predict …

… international prognostic score to predict time to first treatment … log-rank test, ii) more than 20
patients in a node to be considered for … (CD) The bar plot shows the percentage of covariate …

… 20 years, the discovery of novel biomarkers has revolutionized disease prognostication
and treatment prediction… investigated CD20 expression and relative lysis induced by anti-CD20 …

… of the TP53 gene, predict resistance to chemoimmunotherapy … , especially in cells expressing
low levels of CD20.82 In a … patients with high-risk disease features were enrolled, 20 of …

… Higher serum copper level predicts a shorter time to start … with unmutated IGHV genes, CD
38 expression, and CK [71]. … /TP53 mutation and CD49d expression still predicted the inferior …

… Examples include markers predicting treatment response to … associated with decreased
surface CD20 expression in CLL, … Currently, approximately 20% of CLL patients who progressed …

… subgroups of CLL with both different gene expression profiles and different response to
therapy. We then built a robust classifier to predict membership in these subtypes. This classifier …

… is differentially expressed in chronic lymphocytic leukemia and predicts overall survival in …
assigned to the intermediate prognosis subset (hazard ratio [HR] 4·64, 95% CI 1·06–20·18), …

… The best cut-off value of Bax/Bcl-2 ratio to predict the survival, … to identify trustworthy
prognostic markers for CLL [20]. … high levels of Bcl-2 and low levels of Bax protein expression to …