Is plasticity of synapses the mechanism of long-term memory storage?
WC Abraham, OD Jones, DL Glanzman - NPJ science of learning, 2019 - nature.com
… are the principal site of information storage in the brain. This … of hippocampal neurons
that were active during behavioural … is how synaptic enhancement mediated by the non-synaptic …
that were active during behavioural … is how synaptic enhancement mediated by the non-synaptic …
Memory leaks: information shared across memory systems
EM Robertson - Trends in cognitive sciences, 2022 - cell.com
… information between memories. Leaks occur from memories dependent upon hippocampal
… is correlated with the enhanced learning that occurs in the subsequent memory task (task B) …
… is correlated with the enhanced learning that occurs in the subsequent memory task (task B) …
Long‐term plasticity in the hippocampus: maintaining within and 'tagging'between synapses
… late-LTP in different hippocampal subfields. For hippocampal synapses onto CA1 discussed
… allocation onto the same neuron could be enhanced by other mechanisms such as CREB-…
… allocation onto the same neuron could be enhanced by other mechanisms such as CREB-…
Synaptic clustering and memory formation
G Kastellakis, P Poirazi - Frontiers in molecular neuroscience, 2019 - frontiersin.org
… developing hippocampal … enhanced memory and spine clustering of new synapses. Detailed
analysis showed that there are sub-regions of increased synaptic turnover (hotspots) within …
analysis showed that there are sub-regions of increased synaptic turnover (hotspots) within …
Coordinating what we've learned about memory consolidation: Revisiting a unified theory
JD Runyan, AN Moore, PK Dash - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
… The implication is that the rate-limiting step for systems consolidation is the time it … distributed
extra-hippocampal system that comes to coordinate distributed neocortical activity during …
extra-hippocampal system that comes to coordinate distributed neocortical activity during …
Functions of adult-born neurons in hippocampal memory interference and indexing
SM Miller, A Sahay - Nature neuroscience, 2019 - nature.com
… that support memory discrimination, consolidation and clearance. We propose that adult
hippocampal … Third, genetic enhancement of adult hippocampal neurogenesis decreased DGC …
hippocampal … Third, genetic enhancement of adult hippocampal neurogenesis decreased DGC …
Complementary roles of differential medial entorhinal cortex inputs to the hippocampus for the formation and integration of temporal and contextual memory (Systems …
WD Marks, N Yamamoto… - European Journal of …, 2021 - Wiley Online Library
… In humans and rodents, the entorhinal cortical (EC)-hippocampal (HPC) circuit is crucial …
memory information is integrated in HPC cornu ammonis 1 cells. We provide new insights into …
memory information is integrated in HPC cornu ammonis 1 cells. We provide new insights into …
Hippocampal storage and recall of neocortical “What”–“Where” representations
… The aim of this research is to advance understanding of the storage of information from the
neocortex to the hippocampus, and the recall of information back to the neocortex. Key issues …
neocortex to the hippocampus, and the recall of information back to the neocortex. Key issues …
Adult hippocampal neurogenesis for systems consolidation of memory
… First, we consider the functional role of hippocampal neurogenesis for memory clearance in
… synaptic connections [80,81], suggesting that HPC neurogenesis may contribute to memory …
… synaptic connections [80,81], suggesting that HPC neurogenesis may contribute to memory …
Multi-input synapses, but not LTP-strengthened synapses, correlate with hippocampal memory storage in aged mice
… memory only in old mice. Our results reveal how the synaptic basis of hippocampal memory
storage changes with age and suggest that these distinct memory-storing mechanisms may …
storage changes with age and suggest that these distinct memory-storing mechanisms may …