[HTML][HTML] Activated histone acetyltransferase p300/CBP-related signalling pathways mediate up-regulation of NADPH oxidase, inflammation, and fibrosis in diabetic …

AG Lazar, ML Vlad, A Manea, M Simionescu… - Antioxidants, 2021 - mdpi.com
… Based on the important functions of the dysregulated histoneregulator of Nox expression,
ROS production, inflammation, and … of p300/CBP mediates the up-regulation of Nox subtypes, …

[HTML][HTML] … butyrate alleviates lipopolysaccharide-induced inflammatory responses by down-regulation of NF-κB, NLRP3 signaling pathway, and activating histone …

L Jiang, J Wang, Z Liu, A Jiang, S Li, D Wu… - Frontiers in Veterinary …, 2020 - frontiersin.org
… modification that plays important role in the regulation of gene … cell membrane that mediate
activation of the NF-κB signaling … the action of histone acetyltransferase, which facilitates …

Stabilization of the histone acetyltransferase Tip60 by deubiquitinating enzyme USP7 stimulates the release of pro-inflammatory mediators in acute lung injury

J Wang, HY Li, ZB Su - Journal of Molecular Medicine, 2020 - Springer
… its regulation of corresponding cellular inflammatory responses, … inflammation and apoptosis
by inhibiting Tip60 and NF-κBInflammation exerts crucial effects on the progression of ALI […

Histone Acetyltransferase‐Dependent Pathways Mediate Upregulation of NADPH Oxidase 5 in Human Macrophages under Inflammatory Conditions: A Potential …

ML Vlad, SA Manea, AG Lazar, M Raicu… - Oxidative medicine …, 2019 - Wiley Online Library
… The mechanisms of Nox5 regulation are not entirely … the expression pattern of key histone
acetyltransferase subtypes (… an important role in cardiovascular pathology, including NF-κB, …

[HTML][HTML] Epigenetic regulation of inflammatory signaling and inflammation-induced cancer

SYX Tan, J Zhang, WW Tee - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
… and histone variants function in mediating inflammatory responses. … non-histone proteins
such as NF-κB, a key regulator of … An in vitro study illustrated that the histone acetyltransferase

Role of histone deacetylases in monocyte function in health and chronic inflammatory diseases

RM Tordera, M Cortés-Erice - Reviews of Physiology, Biochemistry and …, 2021 - Springer
… process carried out by histone acetyltransferases (HAT) and histone deacetylases (HDAC). …
positive regulator of the inflammatory response induced by the NF-κB pathway playing a key

Integrative function of histone deacetylase 3 in inflammation

J Li, Y Zhai, M Tang - Molecular Biology Reports, 2024 - Springer
… in distinct inflammatory pathway, including NF-κB signaling, … Hence, the precise gene
regulation is crucial for the initiation… complex with acetylated Rel A to mediate the export of Rel A …

[HTML][HTML] TNF-α regulates diabetic macrophage function through the histone acetyltransferase MOF

FM Davis, AD Joshi, SJ Wolf, R Allen, J Lipinski… - JCI insight, 2020 - ncbi.nlm.nih.gov
important role for MOF in regulating macrophage-mediated … the regulation of MOF in
macrophages is unknown. TNF-α is a … that MOF regulates NF-κBmediated inflammatory gene …

[HTML][HTML] HAT/HDAC: The epigenetic regulators of inflammatory gene expression

S Swaroop, A Batabyal… - International Journal …, 2021 - spandidos-publications.com
Histone acetyltransferases (HATs) and histone deacetylases (… of the key regulatory networks
that control NF-κB expression … be crucial for the STAT1-mediated transcription of NF-κB p65(…

[HTML][HTML] Critical functions of histone deacetylases (HDACs) in modulating inflammation associated with cardiovascular diseases

S Kulthinee, N Yano, S Zhuang, L Wang, TC Zhao - Pathophysiology, 2022 - mdpi.com
… action is opposite to that of histone acetyltransferases (HATs). So … and IL-1β-mediated
activation of the NF-κB pathway [55]. … plays an important regulatory role in metabolic inflammatory