… and the second most common neurodegenerative disease (ND) … One critical feature of
astrocytes is to protect the vulnerable … Indeed, within this scenario, DA emerges as a pivotal …

… neurodegenerative disease. Thus, we detail the transcriptional responses initiated by
mitochondrial dysfunction in order to protect … stress pathways initiated by DNA damage which …

… ), an age-related neurodegenerative disorder that is the most … /out of the CNS and to protect
the CNS from peripheral insults [… of Wnt signalling dysregulation between these two scenarios…

… severe neurodegeneration [11]. Similar to other embryonic … signalling pathway confers
some type of protection to the … of mitochondrial events such as mPTP opening, mitochondrial …

… the mitochondria, suggests that the intracellular APP dynamics can also be part of the
pathological scenario … attenuates neuroinflammation and protects against neurodegeneration in a …

… discuss the main signal transduction pathways involved in neurodegenerative disorders. …
How the Wnt signaling pathway protects from neurodegeneration: The mitochondrial scenario. …

… Alzheimer’s disease (AD) is the most common neurodegenerative … -1α was not sufficient to
protect against Aβ-induced NSC … Still, under this scenario, the percentage of viable cells was …

… More complex is the scenario in MS, where cellular metabolism varies according to the activity
… by free radicals, especially mtDNA, since they lack the protection of histone proteins. In a …

… Mitochondria are highly metabolic organelles necessary for … The Wnt signalling pathway
protects microglial synapse … The complex scenario of AD etiopathology suggests that the …

… Amyotrophic lateral sclerosis is a fatal neurodegenerative … , oxidative stress, mitochondrial
dysfunction, neuroinflammation and … In this complex scenario, the identification of other genes …