[HTML][HTML] Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster
Y Higashijima, N Nagai, M Yamamoto… - Communications …, 2020 - nature.com
… Here, we report that Kdm7a −/− mutant mouse exhibits … the expression of Hox genes during
embryogenesis by RNA … , and the sequence domain “HOX” and “Homeobox, conserved site”. …
embryogenesis by RNA … , and the sequence domain “HOX” and “Homeobox, conserved site”. …
Pluripotency factors regulate the onset of Hox cluster activation in the early embryo
… (A) Schematic representation of the four mouse Hox clusters, indicating gene expression …
Asterisks indicate novel intracluster interactions established in dox-treated embryos, and …
Asterisks indicate novel intracluster interactions established in dox-treated embryos, and …
Transgenic strategies for the study of mouse development: an overview
C Babinet - Transgenic Animals, 2022 - taylorfrancis.com
… to control the proper expression of Hox genes during mouse embryonic development. These
… , 1993 and Montoliu et al., 1993, see also the chapter on YAC transgenic mice in this book). …
… , 1993 and Montoliu et al., 1993, see also the chapter on YAC transgenic mice in this book). …
Hox genes in development and beyond
KA Hubert, DM Wellik - Development, 2023 - journals.biologists.com
… During embryogenesis, Hox gene expression becomes … The mouse skeletal system is one
system in which adult Hox … provide important opportunities for novel regenerative therapies. …
system in which adult Hox … provide important opportunities for novel regenerative therapies. …
What are the roles of retinoids, other morphogens, and Hox genes in setting up the vertebrate body axis?
AJ Durston - genesis, 2019 - Wiley Online Library
… I note further that all human and mouse hindbrain Hox genes … during early embryogenesis
(Schyr, Shabtai, Shashikant, & … some novel clues as to how the vertebrate A–P pattern is set …
(Schyr, Shabtai, Shashikant, & … some novel clues as to how the vertebrate A–P pattern is set …
Hox Genes in Reptile Development, Epigenetic Regulation, and Teratogenesis
R Martín-del-Campo, I Sifuentes-Romero… - … and Genome Research, 2019 - karger.com
… during embryonic development; thus, dysregulation of these … been sequenced, and novel
information regarding the … methylation defects at Hox genes in mice expressing a SET domain-…
information regarding the … methylation defects at Hox genes in mice expressing a SET domain-…
[HTML][HTML] HOX genes in stem cells: Maintaining cellular identity and regulation of differentiation
J Steens, D Klein - Frontiers in cell and developmental biology, 2022 - frontiersin.org
… HOX genes, a subset of homeobox genes encoding transcription factors that are generally
… of cell identity and cell fate during embryogenesis, and in maintaining this positional identity …
… of cell identity and cell fate during embryogenesis, and in maintaining this positional identity …
Lysine demethylase 7a regulates the anterior-posterior development in mouse by modulating the transcription of Hox gene cluster
Y Higashijima, N Nagai, T Kitazawa, Y Kawamura… - bioRxiv, 2019 - biorxiv.org
… ”, and the sequence domain “HOX” and “Homeobox, conserved site”. … of the posterior Hox
gene expression, and subsequent … relevant posterior Hox loci in the Kdm7a mutant embryo, we …
gene expression, and subsequent … relevant posterior Hox loci in the Kdm7a mutant embryo, we …
[HTML][HTML] Homeobox genes in cancers: from carcinogenesis to recent therapeutic intervention
Y Feng, T Zhang, Y Wang, M Xie, X Ji, X Luo… - Frontiers in …, 2021 - frontiersin.org
… Recently, novel therapies such as monoclonal antibodies … HOX genes play an essential
role in embryonic development, … to apoptosis in multiple mouse breast cancer derived cell …
role in embryonic development, … to apoptosis in multiple mouse breast cancer derived cell …
[HTML][HTML] Reduced H3K27me3 leads to abnormal Hox gene expression in neural tube defects
J Yu, L Wang, P Pei, X Li, J Wu, Z Qiu, J Zhang… - Epigenetics & …, 2019 - Springer
… mouse embryo, we observed a downward trending for the temporal expression of all Hox
genes… The present study provided novel insight into the synergistic function of transcriptional …
genes… The present study provided novel insight into the synergistic function of transcriptional …