… DNA glycosylases possess only the glycosylase activity, … of systems that repair oxidative
DNA damage would be … under conditions of increased oxidative stress that occur during …

… the repair process by … also participate to protect DNA against oxidative damage, such as
NTH1, MTH1, NEIL1-3, XRCC1 and PARP-1 [57,58,59,60]). Another DNA glycosylase involved …

… Because oxidative damage has been associated with aging and neurodegenerative disease
[61,62] it has been of interest to investigate the role of repair of oxidative DNA lesions on …

… Oxidative stress mostly targets DNA. Continues oxidative damage of the DNA involved in the
… Base-excision repair of oxidative DNA damage by DNA glycosylases. Mutat Res 2005; 591(…

… of oxidative DNA base lesions and the role of DNA glycosylase enzymes repairing these …
the role of DNA base oxidation as an epigenetic mechanism involved in brain diseases, as …

… Moreover, when HeLa cell extracts were incubated with 20 bp cdA substrates, no DNA
glycosylase-mediated cleavage was observed suggesting that human DNA glycosylases cannot …

… Using a borohydride trapping assay, we first verified the activities of several DNA glycosylases,
including the E. coli enzyme Fpg (UniProt ID: P05523) and OGG1 from both human (…

… can either favor cell transformation, tumorigenesis, and/or drug resistance, or instead
sensitize cells to oxidative damage by enhancing the production of toxic BER products [20]. A …

… systems of antioxidant defense and oxidative damage repair in bacteria are now regarded
… In bacteria, several DNA glycosylases are responsible for oxidative damage repair. In E. coli, …

… involved in oxidative damage repair, the H2tH glycosylases represent good candidates for
acquisition from symbiotic mitochondria functionally associated with the evolution of oxidative …