Slotting metabolomics into routine precision medicine
… This review provides the most challenging applications of … metabolism, eliciting many
immediate biochemical changes in … The obtained results are encouraging and promise great …
immediate biochemical changes in … The obtained results are encouraging and promise great …
[HTML][HTML] On the road to accurate biomarkers for cardiometabolic diseases by integrating precision and gender medicine approaches
L Scola, RM Giarratana, S Torre, V Argano… - International journal of …, 2019 - mdpi.com
… been the focus of intricate investigations and false promises, which, until now, have failed to
… well as technical difficulties in integrative modeling that accurately captures true biological …
… well as technical difficulties in integrative modeling that accurately captures true biological …
[HTML][HTML] Imaging and Liquid Biopsy for Distinguishing True Progression From Pseudoprogression in Gliomas, Current Advances and Challenges
K Li, Q Zhu, J Yang, Y Zheng, S Du, M Song, Q Peng… - Academic …, 2024 - Elsevier
… hampered by technical and biological problems such as low … a landmark development in the
medical sector, particularly in … and liquid biopsy hold promise for distinguishing TP from PsP …
medical sector, particularly in … and liquid biopsy hold promise for distinguishing TP from PsP …
[PDF][PDF] Multiscale allostery: basic mechanisms and versatility in diagnostics and drug design
IN Berezovsky, R Nussinov - Journal of Molecular Biology, 2022 - Elsevier
… profiles and improved biochemical and cellular activities. A … A wide spectrum of tasks in
precision medicine relevant to … a great promise for developments in precision medicine. Fauser et …
precision medicine relevant to … a great promise for developments in precision medicine. Fauser et …
[HTML][HTML] High folate, perturbed one-carbon metabolism and gestational diabetes mellitus
… intolerant (a positive response to 1 h glucose challenge but normal oGTT results) and GDM
[… of choline to betaine occurs in the mitochondria, and is catalysed by choline dehydrogenase …
[… of choline to betaine occurs in the mitochondria, and is catalysed by choline dehydrogenase …
[HTML][HTML] Diet-and microbiota-related metabolite, 5-aminovaleric acid betaine (5-AVAB), in health and disease
R Haikonen, O Kärkkäinen, V Koistinen… - Trends in Endocrinology …, 2022 - cell.com
… (MS)-based analytical methods and the increased use of metabolomics approaches have
opened novel avenues to permit a much more detailed molecular-level assessment of human …
opened novel avenues to permit a much more detailed molecular-level assessment of human …
Milk-Derived Extracellular Vesicles: Biomedical Applications, Current Challenges, and Future Perspectives
M Salehi, B Negahdari, F Mehryab… - Journal of Agricultural …, 2024 - ACS Publications
… their challenges and enormous promise as a novel class of theranostics. It is hoped that this
study will pave the way for clinical applications of miEVs by addressing their challenges and …
study will pave the way for clinical applications of miEVs by addressing their challenges and …
Oral delivery of biologics for precision medicine
… design, aiming at confronting each of the biological barriers. The elucidation of their multi-step
mechanism of interaction with the intestinal epithelium opens up new exciting challenges. …
mechanism of interaction with the intestinal epithelium opens up new exciting challenges. …
Skin-interfaced wearable sweat sensors for precision medicine
… the promise of providing noninvasive and continuous insight into the biochemical landscape
… case of burn victims presents new challenges in regenerative wound healing and demands …
… case of burn victims presents new challenges in regenerative wound healing and demands …
[HTML][HTML] Autophagy and Mitophagy as Potential Therapeutic Targets in Diabetic Heart Condition: Harnessing the Power of Nanotheranostics
S Nag, O Mitra, B Maturi, SP Kaur, A Saini… - Asian Journal of …, 2024 - Elsevier
… Autophagy and mitophagy pose unresolved challenges in … Modern medicine places great
emphasis on the application of … , while also discussing the promise of nanotechnology-based …
emphasis on the application of … , while also discussing the promise of nanotechnology-based …