Simultaneous determination of five active alkaloids from Compound Kushen Injection in rat plasma by LC–MS/MS and its application to a comparative …

S Cang, R Liu, T Wang, X Jiang, W Zhang, K Bi… - … of Chromatography B, 2019 - Elsevier
… histological type of lung cancer with high mortality rates, has been … matrine, oxymatrine,
sophoridine, oxysophocarpine and N-… The reduction progress may be catalyzed by microsomal

Insights into oral bioavailability enhancement of therapeutic herbal constituents by cytochrome P450 3A inhibition

J Chen, J Liu, Y Huang, R Li, C Ma… - Drug Metabolism …, 2021 - Taylor & Francis
… In vitro, quercetin greatly reduced the levels of erythromycin-N-demethylation in both intestinal
and liver microsomes, which suggested that CYP3A activity was inhibited (Umathe et al. …