… Endothelial cells display an extraordinary plasticity both … cells or convert into hematopoietic
stem and progenitor cells or … forces that drive these responses. We compare both in vitro and …

… valves. Amongst them, the EndMT process is crucial in generating valve progenitor cells …
, and transformed cells displayed increased capacity for migration in response to endothelin-1 …

… endothelial cells display remarkable phenotypic plasticity (67… cells displayed significantly
enhanced EndMT in response to … miR-126 on EndMT of endothelial progenitor cells (369), the …

… the heterogeneity of EndoMT in response to inflammatory responses remains elusive. …
Further understanding the role of lung endothelial cell plasticity in BPD could uncover novel …

… cells exhibit distinct plasticity, which may provide valve endothelial … cells: partial EndMT-derived
cells showed progenitor cell qualities… to adaptive and maladaptive responses to disease. …

… to the pulmonary vasculature in the early response to hypoxia, and … to inhibit EndMT in
endothelial progenitor cells (203). … Endothelial–mesenchymal transition drives expression of …

… -1, inflammatory response related surface receptors and direct … with differentiation plasticity
[5], which was further shown to … In our model system, we show involvement of this pathway via …

… However, the formation of aortic and pulmonary valves from … of valve progenitor cells and
regulates heart valve formation [19]. As … Normal tricuspid valves did not show such correlations. …

… factor receptor-2]) progenitor cells that originate from cardiac … by the inherent plasticity of
endocardial endothelial cells 4,82 and … in response to TGFβ2 alone, whereas in parallel, human …

… effects of VICs on human endothelial progenitor cells and the subsequent signaling …
Specific contribution of these cells to valve plasticity during both homeostasis and response …