… It is important to note that incorporation of modifications within the binding motifs of aptamer
… In addition to serving as the sole hybridization partner for a natural oligonucleotide, …

… triplex I motif or parallel triplex, an oligonucleotide made of cyto… or PNA openers that facilitates
hybridization by binding to the … stable oligonucleotide-directed triple helix formation at the …

… at the promotor region can induce either inhibition or activation effect depending on the triplex
motif (… 8), which permits the donor DNA to hybridize the target DNA. Finally, the homology-…

… Triple helical nucleic acids are generated by the binding of a third oligonucleotide strand within
the … available for complementary DNA hybridization, linking the component tiles together. …

… for introducing these modifications into oligonucleotides. … to a broad variety of base-modified
nucleoside analogues. … recognition, folding, and hybridization properties. A treatment with a …

… hybridization studies reveal for the first time that this type of cationic/amino-alkyl base-modified
PNA has favorable hybridization properties … affinity for oligonucleotide hybridization at 37 …

… The hybridization of all the synthesized TFOs with a target DNA duplex was … oligonucleotides
able to bind a oligopurine segment of a DNA duplex with formation of a DNA triple helix (H-…

… This results in the formation of three triplex motifs, depending on their base composition and
… This is different from xylo-LNA, which had a negative effect on the hybridization properties …

… with protein-like side chain motifs such as histamine, arginine, … a wide spectrum of base-modified
nucleotides including the … on the chemical synthesis and hybridization properties of N4-…

… to degradation by nucleases while maintaining similar hybridization properties than
unmodified oligonucleotides [210]. The addition of a syn -norspermidine group at position 5 of 2󸀠-…