Hypoxia-modified cancer cell metabolism
W Al Tameemi, TP Dale, RMK Al-Jumaily… - Frontiers in cell and …, 2019 - frontiersin.org
… understanding of cancer cell survival… hypoxia-instigated modifications in cancer cell metabolism
and exemplifies the correlation between metabolic change and its support of the hypoxic-…
and exemplifies the correlation between metabolic change and its support of the hypoxic-…
Cancer cell metabolism in hypoxia: role of HIF-1 as key regulator and therapeutic target
V Infantino, A Santarsiero, P Convertini… - International journal of …, 2021 - mdpi.com
… in the adaption of cancer cell metabolism to hypoxia, a process that is essential to promote
cancer cell survival, proliferation, and metastasis. The impact of hypoxia is particularly evident …
cancer cell survival, proliferation, and metastasis. The impact of hypoxia is particularly evident …
Metabolic adaptation in hypoxia and cancer
F Paredes, HC Williams, A San Martin - Cancer letters, 2021 - Elsevier
… by cancer cells to promote glycolytic metabolism to support biomass synthesis for … metabolic
reprogramming under hypoxia benefits tumor growth and metastasis, many cancer cells …
reprogramming under hypoxia benefits tumor growth and metastasis, many cancer cells …
Hypoxia and metabolism in metastasis
T Zhang, C Suo, C Zheng, H Zhang - Hypoxia and cancer metastasis, 2019 - Springer
… cancer cell metabolism and metastasis regulated by hypoxia. … have shown that hypoxic
cancer cells absorb acetate from … -CoA is utilized for anabolic metabolism including the de novo …
cancer cells absorb acetate from … -CoA is utilized for anabolic metabolism including the de novo …
Oxidative stress in cancer cell metabolism
… Cancer cells are highly metabolically active and hypoxic cells, and due to massive growth
and insufficient vascular irrigation tend to produce increased ROS, which damages DNA by …
and insufficient vascular irrigation tend to produce increased ROS, which damages DNA by …
HIF-1-independent mechanisms regulating metabolic adaptation in hypoxic cancer cells
… , we postulate that cancer cell metabolic plasticity and redundancies in metabolic regulatory
… be sufficient to disrupt the metabolism of cancer cells and produce meaningful clinical benefit…
… be sufficient to disrupt the metabolism of cancer cells and produce meaningful clinical benefit…
Lipid metabolism in cancer cells under metabolic stress
… deprivation limit cancer cells’ metabolic flexibility that otherwise allows these cells to switch
… The expression of PNPLA2 in hypoxic cancer cells remains unchanged; instead, PNPLA2 …
… The expression of PNPLA2 in hypoxic cancer cells remains unchanged; instead, PNPLA2 …
Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia
Y Wang, C Bai, Y Ruan, M Liu, Q Chu, L Qiu… - Nature …, 2019 - nature.com
… , re-building a new coordinative metabolism is required. Here we show that hypoxia alters
glutamine metabolism and drives a new metabolic homeostasis of its carbon and nitrogen. …
glutamine metabolism and drives a new metabolic homeostasis of its carbon and nitrogen. …
Metabolism of immune cells in cancer
RD Leone, JD Powell - Nature reviews cancer, 2020 - nature.com
… of immune cell metabolism and cancer metabolism has grown … interaction of cancer cell
metabolism and immune metabolism in … and hypoxic microenvironment, establishing metabolic …
metabolism and immune metabolism in … and hypoxic microenvironment, establishing metabolic …
Hypoxia/pseudohypoxia‐mediated activation of hypoxia‐inducible factor‐1α in cancer
Y Hayashi, A Yokota, H Harada, G Huang - Cancer science, 2019 - Wiley Online Library
… The identification of hypoxic cells in tumors by Thomlinson and Gray … metabolism in cancer
cells.2, 3 Hypoxic conditions could induce HIF1A, a master regulator of glucose metabolism, …
cells.2, 3 Hypoxic conditions could induce HIF1A, a master regulator of glucose metabolism, …
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