… understanding of cancer cell survival… hypoxia-instigated modifications in cancer cell metabolism
and exemplifies the correlation between metabolic change and its support of the hypoxic-…

… in the adaption of cancer cell metabolism to hypoxia, a process that is essential to promote
cancer cell survival, proliferation, and metastasis. The impact of hypoxia is particularly evident …

… by cancer cells to promote glycolytic metabolism to support biomass synthesis for … metabolic
reprogramming under hypoxia benefits tumor growth and metastasis, many cancer cells …

… cancer cell metabolism and metastasis regulated by hypoxia. … have shown that hypoxic
cancer cells absorb acetate from … -CoA is utilized for anabolic metabolism including the de novo …

… Cancer cells are highly metabolically active and hypoxic cells, and due to massive growth
and insufficient vascular irrigation tend to produce increased ROS, which damages DNA by …

… , we postulate that cancer cell metabolic plasticity and redundancies in metabolic regulatory
… be sufficient to disrupt the metabolism of cancer cells and produce meaningful clinical benefit…

… deprivation limit cancer cells’ metabolic flexibility that otherwise allows these cells to switch
… The expression of PNPLA2 in hypoxic cancer cells remains unchanged; instead, PNPLA2 …

… , re-building a new coordinative metabolism is required. Here we show that hypoxia alters
glutamine metabolism and drives a new metabolic homeostasis of its carbon and nitrogen. …

… of immune cell metabolism and cancer metabolism has grown … interaction of cancer cell
metabolism and immune metabolism in … and hypoxic microenvironment, establishing metabolic …

… The identification of hypoxic cells in tumors by Thomlinson and Gray … metabolism in cancer
cells.2, 3 Hypoxic conditions could induce HIF1A, a master regulator of glucose metabolism, …