The expressions of TSLP, IL-33, and IL-17A in monocyte derived dendritic cells from asthma and COPD patients are related to epithelial–macrophage interactions

M Paplinska-Goryca, P Misiukiewicz-Stepien… - Cells, 2020 - mdpi.com
… -4, IL-5, IL-13) and TNF-α but downregulated IL-10 and interferon … , and IL-17A mRNA
expression in moDCs after IL-13 or poly I:… TNF-α mRNA expression in moDCs after IL-13 or poly …

Regulation of filaggrin, loricrin, and involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: pathogenic implications in atopic dermatitis

M Furue - International journal of molecular sciences, 2020 - mdpi.com
… In addition to IL-4 and IL-13, IL-22 and IL-17A are probably … As IL-4, IL-13, IL-22, and IL-17A
are all capable of inducing … IVL expression is regulated by IL-4, IL-13, IL-22, and IL-17A. The …

Molecular switches for regulating the differentiation of inflammatory and IL-10-producing anti-inflammatory T-helper cells

D Fang, J Zhu - Cellular and Molecular Life Sciences, 2020 - Springer
… , IL-13 increases IL-10 production but only in polarized Th17 … Although IL-10 is difficult to
be detected in human Th17 cells … Th17 cell clones can produce IL-10, and both IL-10 + IL-17A

The role of Th17-related cytokines in atopic dermatitis

M Sugaya - International journal of molecular sciences, 2020 - mdpi.com
… cytokines such as IL-4 and IL-13 are regarded to be the main … IL-17A expression was
significantly increased in the involved … , IL-5, IL-13, and TNF-α, while down-regulating IL-10 and …

Regulation of IL-17A and implications for TGF-β1 comodulation of airway smooth muscle remodeling in severe asthma

JM Evasovic, CA Singer - American Journal of Physiology …, 2019 - journals.physiology.org
regulated by T H 2- and macrophage-derived IL-10 through an IL-13-dependent
mechanism, restraining IL-17A-… IL-10, which is also secreted by T REG cells, is an anti-inflammatory …

[HTML][HTML] High-dose IL-2 skews a glucocorticoid-driven IL-17+ IL-10+ memory CD4+ T cell response towards a single IL-10–producing phenotype

EH Mann, L Gabryšová, PE Pfeffer… - The Journal of …, 2019 - journals.aai.org
… To better understand these seemingly opposing effects of glucocorticoids on the induction
of IL-10 and IL-17A, this study sought to characterize the cellular source of glucocorticoid-…

IL-17A both initiates, via IFNγ suppression, and limits the pulmonary type-2 immune response to nematode infection

J Ajendra, AL Chenery, JE Parkinson, BHK Chan… - Mucosal …, 2020 - nature.com
… For example, IL-17A contributes to asthma pathology by enhancing IL-13 activity 25 and a
… The concentrations of IL-5, IL-6, IL-9, IL-10, IL-13, IL-17A, TNFα and IFNγ in the mLN culture …

IL-17A–A regulator in acute inflammation: Insights from in vitro, in vivo and in silico studies

V Sud, A Abboud, S Tohme, Y Vodovotz, RL Simmons… - Cytokine, 2021 - Elsevier
… as IL-2, IL-4, IL-13, and IL-17A. As time progressed, the network of interactions between the
innate and lymphoid inflammatory mediators became more complex. This analysis identified …

The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases

V Navarro-Compán, L Puig, S Vidal, J Ramírez… - Frontiers in …, 2023 - frontiersin.org
… -5, and IL-13 and respond against parasites and allergens; and T reg for TGF-β and IL-10
and … determines the differentiation of Th17 cells, inducing the production of IL-17A and IL-17F, …

[HTML][HTML] AT cell–myeloid IL-10 axis regulates pathogenic IFN-γ–dependent immunity in a mouse model of type 2–low asthma

WJ Branchett, H Stölting, RA Oliver, SA Walker… - Journal of Allergy and …, 2020 - Elsevier
… induced a mixed IL-13/IL-17A response and accumulation of IL-10–producing forkhead box
… –derived IL-10 increased the IFN-γ and IL-17A response to HDM, reducing IL-13 levels and …