… Cytotoxicity and interferon-γ production of CD8 + T cells from peripheral blood and CSF was
also augmented in response to IL-7 … Perforin and granzyme was pore-forming molecules, …

… mRNA expression of 51 ISGs was assessed using RT-qPCR and cytokine production …
IL-10 protein expression could distinguish LTBI from ATB. FCGR1A, IFIT1 and IL-10 genes drive …

… Proposed model of cytotoxic T-lymphocytes that contains two … evolves by impacting the
expression and function of various … not only by its gene expression profile but also by altered …

… the theoretical role of IL-7 to restore lymphocyte repertoire, as … , through the cleavage of the
pore-forming gasdermin-D [32,35… skew naïve T-cells to Th1 or cytotoxic lymphocytes (CTLs or …

… interferon- γ (IFN- γ ) increased synchronously (p < 0.05). Levels of interleukin-2 (IL-2) and
Pore-forming protein (… effector T cells, while IL-7 and IL-15 promote the expansion of primitive …

… through secretion of the pore-forming molecule perforin and … may include increased production
of interferon-γ (IFNγ) and … In the cancer context, we have shown that IL-7 expression in …

… of effector T cells. Traditionally, it was believed that immunotherapy-activated CD8+ T cells
… However, many studies have surprisingly revealed that CD8+ T cells can suppress tumors …

… The combined action of the pore-forming antimicrobial protein … IL-2 + IL-7 for 2 d to allow
up-regulation of cytotoxic molecules [24,… As Gnly is similarly expressed late by cytotoxic T cells …

… increases the expression of cation-selective pore-forming proteins, … the IL-7-STAT5 axis, of
which the target genes change … effectiveness by boosting interferon-γ-mediated signaling and …

… HSC by regulation of multiple cytokines (IL-3 and IL-7) and … interferon γ (IFN-γ), and hence
modulate immune-regulatory … transforming CD8 + T cells into cytotoxic T lymphocytes (CTLs)…