RstA is a major regulator of Clostridioides difficile toxin production and motility
… Through mutational analysis of the rstA promoter, we identified … binds and regulates the
promoters of the toxin genes tcdA … unlikely that the extracellular AIP molecule directly interacts …
promoters of the toxin genes tcdA … unlikely that the extracellular AIP molecule directly interacts …
Pathogenicity and virulence of Clostridium perfringens
I Mehdizadeh Gohari, M A. Navarro, J Li, A Shrestha… - Virulence, 2021 - Taylor & Francis
… perfringens toxins is highly regulated via processes involving … of toxins and extracellular
degradative enzymes produced by … loci on large tcp-conjugative plasmids suggests that the toxin …
degradative enzymes produced by … loci on large tcp-conjugative plasmids suggests that the toxin …
Detection and Molecular Identification of Salmonella Virulence Genes in Livestock Production Systems in South Africa
TP Mthembu, OT Zishiri, ME El Zowalaty - Pathogens, 2019 - mdpi.com
… via encoded T3SS since they harbor host invasion and intracellular survival genes [29,32]. …
iroB, a Fur-regulated gene located in a large DNA region which is used in the detection of S. …
iroB, a Fur-regulated gene located in a large DNA region which is used in the detection of S. …
Staphylococcal biofilm development: structure, regulation, and treatment strategies
K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
… the production of extracellular toxins and enzymes (244… that Rot can potentially regulate all
four protease loci, but the degree … The idea is to identify molecules that specifically target the …
four protease loci, but the degree … The idea is to identify molecules that specifically target the …
Good gone bad: one toxin away from disease for Bacteroides fragilis
E Valguarnera, JB Wardenburg - Journal of molecular biology, 2020 - Elsevier
… the active C-terminal domain into the extracellular milieu [74,75]. … Studies on the genetic
locus that encodes BFT have been … controls transcription [94]. A key mechanism for control of …
locus that encodes BFT have been … controls transcription [94]. A key mechanism for control of …
The new genetic landscape of Alzheimer's disease: from amyloid cascade to genetically driven synaptic failure hypothesis?
… this major genetic component, identification of the genetic risk … genetic analyses have pointed
out more than 45 genes/loci … suggest that ApoE regulates extracellular Aβ clearance in the …
out more than 45 genes/loci … suggest that ApoE regulates extracellular Aβ clearance in the …
The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
AM Geller, I Pollin, D Zlotkin, A Danov… - Nature …, 2021 - nature.com
… we identify eCIS loci in 1,249 bacterial and archaeal genomes and reveal an enrichment of
these loci … , Tse2 50 , as a positive control, and two negative controls: a monomeric enhanced …
these loci … , Tse2 50 , as a positive control, and two negative controls: a monomeric enhanced …
In vitro and in vivo biofilm forming Vibrio spp: a significant threat in aquaculture
M Arunkumar, F LewisOscar, N Thajuddin… - Process …, 2020 - Elsevier
… with the self-production of extracellular polysaccharides (EPS). … aquaculture have been
identified, analyzed and documented … vulnificus, wcr locus regulates the EPS production and the …
identified, analyzed and documented … vulnificus, wcr locus regulates the EPS production and the …
Endo-lysosomal dysregulations and late-onset Alzheimer's disease: impact of genetic risk factors
ZP Van Acker, M Bretou, W Annaert - Molecular neurodegeneration, 2019 - Springer
… , production and concentration of intracellular toxic Aβ42 … Aβ aggregation to higher
molecular weight species capable of … One study detected CD2AP to be a susceptibility locus for …
molecular weight species capable of … One study detected CD2AP to be a susceptibility locus for …
Regulation of Staphylococcus aureus Virulence
C Jenul, AR Horswill - Microbiology spectrum, 2019 - Am Soc Microbiol
… surface adhesins and extracellular enzymes and toxins. Of these … Alpha-toxin is one of the
most prominent regulated toxins … rot locus in an agr-null background restores toxin production …
most prominent regulated toxins … rot locus in an agr-null background restores toxin production …