Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy

J Shang, L Wang, Y Zhang, S Zhang… - Journal of cellular …, 2019 - Wiley Online Library
… The aim of this study was to identify the function of chemerin/ChemR23 in GEnCs in DN …
-shRNA-ChemR23 could rescue HG or chemerin-induced endothelial injury and inflammation. …

Chemerin-9, a potent agonist of chemerin receptor (ChemR23), prevents atherogenesis

K Sato, H Yoshizawa, T Seki, R Shirai… - Clinical …, 2019 - portlandpress.com
… adhesion molecule-1 (VCAM1), and E-selectin, in endothelial cells (ECs). These effectors
… Proteins were visualized by enhanced chemiluminescence Western blotting detection

[HTML][HTML] Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells

L Jun, S Lin-Lin, S Hui - Molecular Vision, 2021 - ncbi.nlm.nih.gov
… the chemerin-induced migration of vascular smooth muscle cells … of the chemerin/ChemR23
pathway in RRMECs identified in this … are composed of pericytes and endothelial cells. DR is …

Role of Chemerin/ChemR23 axis as an emerging therapeutic perspective on obesity-related vascular dysfunction

Y Xie, L Liu - Journal of translational medicine, 2022 - Springer
… , which is concretely embodied in a 37% similar sequence identity between them [36]. That
… in human aorta endothelial cells with chemerin stimulation, and the chemerin-induced ROS …

Chemerin induced by Treponema pallidum predicted membrane protein Tp0965 mediates the activation of endothelial cell via MAPK signaling pathway

RL Zhang, QQ Wang, LJ Yang - Journal of Cellular …, 2019 - Wiley Online Library
chemerin, a recently identified … of chemerin and ChemR23 in endothelial cells To investigate
the involvement of Tp0965 in the expression of chemerin and ChemR23 in endothelial cells

Chemerin in atherosclerosis

JX Sun, C Zhang, ZB Cheng, MY Tang, YZ Liu… - Clinica Chimica …, 2021 - Elsevier
… , elevating endothelial cell adhesion molecule endothelial … and defective chemerin-induced
transmigration in ChemR23 … lipoprotein cholesterol, identifying chemerin as a potential risk …

SP453 Role of Chemerin/ChemR23 during injury of glomerular endothelial cells of diabetic nephropathy

S Jing, Y Dou, C Genyang, L Dong… - Nephrology Dialysis …, 2019 - academic.oup.com
endothelial marker CD31. Both LV3-shRNA and SB203580 (p38 MAPK inhibitor) attenuated
chemerin-induced … Here, we aim to identify key lncRNAs of DN using bioinformatics and …

Chemerin inhibits vascular calcification through ChemR23 and is associated with lower coronary calcium in chronic kidney disease

M Carracedo, A Witasp, AR Qureshi… - Journal of Internal …, 2019 - Wiley Online Library
… these identified confounders into consideration, chemerin remained … chemerin-induced
effects on calcification in VSMC lacking the ChemR23 receptor indeed supports that ChemR23

Chemerin in inflammatory diseases

X Su, Y Cheng, G Zhang, B Wang - Clinica Chimica Acta, 2021 - Elsevier
… by reacting with the ChemR23 receptor. In various … identify two other chemerin receptors,
as G protein-coupled … the influence on epithelial cell proliferation and creating new capillaries. …

The role of Chemerin in human diseases

G Yue, Q An, X Xu, Z Jin, J Ding, Y Hu, Q Du, J Xu… - Cytokine, 2023 - Elsevier
Chemerin is an inflammatory chemokine, originally identified … The Chemerin/ChemR23 axis
plays a role in epithelial injury … Chemerin-induced migration of pulmonary and thoracic aortic …