Methyl‐sensing nuclear receptor liver receptor homolog‐1 regulates mitochondrial function in mouse hepatocytes
… Another report identifying glucokinase as a primary LRH‐1 target links LRH‐1 to glucose …
LRH‐1 target genes, including apolipoprotein A1 (Apoa1), scavenger receptor class B member …
LRH‐1 target genes, including apolipoprotein A1 (Apoa1), scavenger receptor class B member …
[HTML][HTML] Emerging functions of the nuclear receptor LRH-1 in liver physiology and pathology
Y Sun, H Demagny, K Schoonjans - … Acta (BBA)-Molecular Basis of Disease, 2021 - Elsevier
… (LRH-1, NR5A2), originally identified in the liver as a regulator of … Another example is liver
receptor homolog 1 (LRH-1, also … Apolipoprotein A1 (ApoA1), the major protein component of …
receptor homolog 1 (LRH-1, also … Apolipoprotein A1 (ApoA1), the major protein component of …
Regulation of the apolipoprotein M signaling pathway: a review
G Cheng, L Zheng - Journal of Receptors and Signal Transduction, 2022 - Taylor & Francis
… receptor, small heterodimer partner, liver receptor homolog-1… transcription factor for gene
expression in the intestine, liver, and … [Citation22] were the first to identify apoM expression in …
expression in the intestine, liver, and … [Citation22] were the first to identify apoM expression in …
Evaluating the effects of PCBs in non-alcoholic fatty liver disease & diabetes and the role of AhR in regulating the hepatic proteome and lipid metabolism.
J Jin - 2020 - ir.library.louisville.edu
… fatty liver disease and novel mechanisms for PCBs in fatty liver disease were identified, like
the PNPLA3 gene: … While tumors were not observed in the present study, the identification of …
the PNPLA3 gene: … While tumors were not observed in the present study, the identification of …
[HTML][HTML] Peroxisome Proliferator-Activated Receptor α in Lipoprotein Metabolism and Atherosclerotic Cardiovascular Disease
EV Fuior, E Zvintzou, T Filippatos, K Giannatou… - Biomedicines, 2023 - mdpi.com
… Initially identified as xenobiotic-induced molecules with the … The APOA1 gene is present
in the APOA1/C3/A4/A5 gene … Liver receptor homolog-1 (LRH-1) [65], forkhead box A2 (…
in the APOA1/C3/A4/A5 gene … Liver receptor homolog-1 (LRH-1) [65], forkhead box A2 (…
Unveiling the Hub Genes Associated with Manganese-Induced Hepatotoxicity
B Yang, Z Hu, S Wang, X Shi, X Li - 2023 - researchsquare.com
… Thus, the objective of this study was to identify the key genes … the gene expression data
set GSE59923 from the Gene … the gene expression data of MnCl2-treated and control liver …
set GSE59923 from the Gene … the gene expression data of MnCl2-treated and control liver …
mTORC1-dependent protein synthesis and autophagy uncouple in the regulation of Apolipoprotein AI expression
K Georgila, M Gounis, S Havaki, VG Gorgoulis… - Metabolism, 2020 - Elsevier
… of APOA1 transcription in tissues other than the liver and … for ApoA-I regulation, we performed
gene silencing of Beclin1 … We thus embarked on studies aiming to identify factors that are …
gene silencing of Beclin1 … We thus embarked on studies aiming to identify factors that are …
Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis
H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
… representing the most common chronic liver disease in the world. … The liver is the major
organ for cholesterol metabolism. … of research aimed at identifying key molecules and cellular …
organ for cholesterol metabolism. … of research aimed at identifying key molecules and cellular …
[HTML][HTML] The role of the retinoid receptor, RAR/RXR heterodimer, in liver physiology
B Li, SY Cai, JL Boyer - Biochimica et Biophysica Acta (BBA)-Molecular …, 2021 - Elsevier
… liver receptor homolog-1 … [50] first reported that retinoids stimulate Apo AI expression in
HepG2 cells. At least three RAREs have been identified in the apoA-I promoter. One of the RARE …
HepG2 cells. At least three RAREs have been identified in the apoA-I promoter. One of the RARE …
[HTML][HTML] The roles of nuclear receptors in cholesterol metabolism and reverse cholesterol transport in nonalcoholic fatty liver disease
Z Li, D Zheng, T Zhang, S Ruan, N Li, Y Yu… - Hepatology …, 2024 - journals.lww.com
… Furthermore, mutations in the genes regulating cholesterol … in metabolism, sex determination,
reproductive development, … for cholesterol efflux from cells to apolipoprotein AI (apoA-I) …
reproductive development, … for cholesterol efflux from cells to apolipoprotein AI (apoA-I) …