[HTML][HTML] Impact of DNA methylation of the human mesoderm-specific transcript (MEST) on male infertility

T Amjadian, P Yaghmaei, HR Nasim, K Yari - Heliyon, 2023 - cell.com
… Likewise, aberrant expression of the MEST gene is responsible for some forms of male
infertility. In previous studies, oligozoospermic men and those with idiopathic infertility have …

[HTML][HTML] Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
aberrantly methylated in altered sperm samples from infertile … in idiopathic infertile males,
especially in oligozoospermic … to be characterized, thereby greatly improving the current …

[HTML][HTML] Poor semen parameters are associated with abnormal methylation of imprinted genes in sperm DNA

B Song, Y Chen, C Wang, G Li, Z Wei, X He… - Reproductive Biology …, 2022 - Springer
… due to the aberrant imprinting in spermatozoa of infertile men [8]. … with idiopathic infertility is
associated with abnormal DNA … Therefore, the role of DNA methylation in male infertility and …

Methylation levels of IGF2 and KCNQ1 in spermatozoa from infertile men are associated with sperm DNA damage

W Ni, C Pan, Q Pan, Q Fei, X Huang, C Zhang - Andrologia, 2019 - Wiley Online Library
… Our results suggest that the aberrant methylation of IGF2 and … diagnosed with unexplained
or idiopathic infertility, and those … strong correlation between abnormal methylation of H19 and …

[HTML][HTML] Epigenetic modifications, a new approach to male infertility etiology: a review

ET Marzouni, H Ilkhani, AB Harchegani… - … of Fertility & Sterility, 2022 - ncbi.nlm.nih.gov
… of IGF2⁄H19-ICR1 and MEST has a correlation with low … MEST can be associated with
idiopathic male infertility. Therefore, aberrant MEST methylation can be considered as a strong

Aberrant epigenetics and reproductive disorders

U Abur, S Gunes - Epigenetics and Reproductive Health, 2021 - Elsevier
… , strong association have been reported between aberrant … In this meta-analysis, the
methylation levels of MEST and SNRPN … gene abnormalities in idiopathic infertility remains …

[HTML][HTML] The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis

E Leitão, S Di Persio, S Laurentino, M Wöste… - Clinical …, 2020 - Springer
… that male infertility itself is associated with aberrant DNA … , which was highly correlated with
the aberrant methylation in … the prevalence of aberrant methylation in infertile men has likely …

Role of genetics and epigenetics in male infertility

S Gunes, SC Esteves - Andrologia, 2021 - Wiley Online Library
… in both idiopathic and unexplained infertility. … methylation characteristics in male infertility
phenotypes has increased steadily. A strong association has been reported between aberrant

DNA methylation defects in spermatozoa of male partners from couples experiencing recurrent pregnancy loss

K Khambata, S Raut, S Deshpande… - Human …, 2021 - academic.oup.com
… in this study could contribute to aberrant methylation patterns in the resulting … methylation
and aberrant imprinting patterns in sperm of men whose partners have experienced idiopathic

[HTML][HTML] The prolonged disease state of infertility is associated with embryonic epigenetic dysregulation

MM Denomme, ME Haywood, BR McCallie… - … and Sterility, 2021 - Elsevier
… susceptible to methylation alterations upon prolonged infertility, … Several signaling pathways
were highly represented among … The detection of aberrant imprinted methylation may be an …