Establishment of mouse androgenetic embryonic stem cells by double sperm injection and differentiation into beating embryoid body

L Lei, L Hu, T Li, X Shen, X Liang, Y Chen, X Feng… - Zygote, 2019 - cambridge.org
Parthenogenetic and androgenetic haploid ESCs are very … Gtl2 and Igf2r were expressed
at levels equivalent to those in … correlation between the expression of H19 and Igf2 in AgES …

Loss of imprinting of the Igf2-H19 ICR1 enhances placental endocrine capacity via sex-specific alterations in signalling pathways in the mouse

BRL Aykroyd, SJ Tunster, AN Sferruzzi-Perri - Development, 2022 - journals.biologists.com
… genomes (androgenetic) or two maternal genomes (parthenogenetic or gynogenetic) … , we
quantified the abundance of Igf2 receptors (Igf1r, Igf2r, Insr) and downstream members of the …

[HTML][HTML] Dysregulated gene expression of imprinted and X-linked genes: a link to poor development of bovine haploid androgenetic embryos

L Aguila, J Suzuki, ABT Hill, M García… - Frontiers in Cell and …, 2021 - frontiersin.org
… For instance, during preimplantation development the maternal … Diploid androgenetic and
gynogenetic/parthenogenetic … In contrast, while the transcripts of the IGF2R imprinted gene

Genomic imprinting: a paradigm for epigenetics of human diseases

RM John, L Lefebvre, MA Surani - Epigenetic Epidemiology, 2022 - Springer
… the Igf2 gene also on the paternal allele which, in the case of Igf2, … the maternally-expressed
Igf2r gene, whereby truncation of the … only in preimplantation embryos and extra-embryonic …

Role of genomic imprinting in mammalian development

T Thamban, V Agarwaal, S Khosla - Journal of biosciences, 2020 - Springer
… cDNA screen of androgenetic and parthenogenetic embryos, … such as Snrnpn, Igf2r, U2af1-rs1
genes exhibit allele-specific … transiently in pre-implantation embryo, with only a few genes

Genetic marker exploration of fertility genes IGF 1 and IGF 2 at Ongole Cross breed cattle with naturally twin birth

W Li, SH Garofalini, L Shapiro, E Elsangeedy, H Lee - iopscience.iop.org
… [6] Latham KE, Adam SD, Carolyn DS and Richard MS 1993 Igf2r and Igf2 gene expression
in androgenetic, gynogenetic, and parthenogenetic preimplantation mouse embryos: …

Haploid androgenetic development of bovine embryos reveals imbalanced WNT signaling and impaired cell fate differentiation

L Aguila, RP Nociti, RV Sampaio… - Biology of …, 2023 - academic.oup.com
… Moreover, it is known that already at the preimplantation … Also, IGF2R, which has been
shown to be expressed biallelically in humans, was more expressed in ICSI and parthenogenetic

Abnormal offspring syndrome

RM Rivera, CG Donnelly, BN Patel, Y Li… - Bovine …, 2021 - Wiley Online Library
… , in which androgenetic and gynogenetic mouse embryos … IGF2R is maternally expressed
and its protein binds to IGF2 … or late stage of preimplantation development. Theriogenology …

[HTML][HTML] Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

RAM Dirks, G Van Mierlo, HHD Kerstens… - Epigenetics & …, 2019 - Springer
… mice (derived from two paternal pronuclei) and gynogenetic mice (… With regard to
parthenogenesis, ESC-PGA cells were … we also find monoallelic expression of Igf2r in the B6D2F1 …

[HTML][HTML] Genomic imprinting and physiological processes in mammals

V Tucci, AR Isles, G Kelsey, AC Ferguson-Smith… - Cell, 2019 - cell.com
… (Igf2r) locus on mouse chromosome 17, which is expressed … but downstream of Igf2, the
non-coding RNA H19 gene was … chimeras containing gynogenetic or androgenetic cells mixed …