Targeting PD-1/PD-L1 axis as new horizon for ovarian cancer therapy

E Khatoon, D Parama, A Kumar, MS Alqahtani… - Life Sciences, 2022 - Elsevier
Ovarian cancer is one of the deadliest gynecological cancers and the 7th most commonly
occurring cancer in women globally. The 5 year survival rate is estimated to be less than 25 %, …

Dendritic cell-derived exosomes: a new horizon in personalized cancer immunotherapy?

F Ghorbaninezhad, H Alemohammad, B Najafzadeh… - Cancer Letters, 2023 - Elsevier
Dendritic cells (DCs) release nanometer-sized membrane vesicles known as dexosomes,
containing different molecules, particularly proteins, for presenting antigens, ie, major …

Immunotherapy in prostate cancer: new horizon of hurdles and hopes

I Tsaur, MP Brandt, E Juengel, C Manceau… - World journal of …, 2021 - Springer
Purpose Prostate cancer (PCa) is the most common malignancy in men and the cause for
the second most common cancer-related death in the western world. Despite ongoing …

Exosomes in hepatocellular carcinoma: a new horizon

R Chen, X Xu, Y Tao, Z Qian, Y Yu - Cell Communication and Signaling, 2019 - Springer
Exosomes are a class of extracellular vesicles released by multiple cells types including
tumor cells, with a size range of 30-100 nm and a lipid bilayer membrane. Recently, the role of …

The glymphatic system: a novel component of fundamental neurobiology

LM Hablitz, M Nedergaard - Journal of Neuroscience, 2021 - Soc Neuroscience
system is the analog of the lymphatic system in the CNS. As such, the glymphatic system
Much remains to be studied, but we propose that the glymphatic/lymphatic system acts as a …

Circulating tumor cells in bladder cancer: A new horizon of liquid biopsy for precision medicine

F Crocetto, A Cimmino, M Ferro… - Journal of Basic and …, 2022 - degruyter.com
Clinical management of bladder cancer (BC) patients offers several challenges such as
poor outcome because of elevated recurrence rates and lack of response to chemotherapy [1]. …

Herbal mediated silver nanoparticles: A new horizon of antineoplastic drug delivery system

SV Rao, S Naserunnisa, K Padmalatha - Journal of Drug Delivery …, 2019 - jddtonline.info
… Apart from therapeutic benefits, metal NPs are also used as a diagnostic tool for the imaging
of cancer cells15. Metal NPs based therapeutic systems not only provide simultaneous …

Aging and immunotherapies: New horizons for the golden ages

JAG Hamilton, CJ Henry - Aging and cancer, 2020 - Wiley Online Library
… Immunotherapies are a new drug class that has revolutionized our ability to treat previously
intractable cancers; however, their efficacy in patients with compromised immune systems

New horizons in bladder cancer research

JL Boormans, EC Zwarthoff, PC Black… - … Oncology: Seminars and …, 2020 - Elsevier
imaging techniques (eg, photodynamic diagnosis (PDD)), we developed a real-time multispectral
imaging (rMSI) device, enabling simultaneous imaging … , narrow band imaging (NBI)-…

Multiphoton intravital microscopy of mandibular draining lymph nodes: a mouse model to study corneal immune responses

MJ Lopez, Y Seyed-Razavi, T Yamaguchi… - Frontiers in …, 2020 - frontiersin.org
… to image cells in vivo. Its application in immunology research has opened new horizons,
allowing intravital imaging of … intravital imaging, while nerves, blood, and lymphatic vessels were …