[HTML][HTML] Chronic liver disease in humans causes expansion and differentiation of liver lymphatic endothelial cells

BAJ Tamburini, JM Finlon, AE Gillen, MS Kriss… - Frontiers in …, 2019 - frontiersin.org
immunofluorescence analysis we identified liver lymphatic endothelial cells and found that
chronic liver … and in primary endothelial cell cultures confirming that these subsets are of …

[HTML][HTML] Single-cell transcriptomics reveals zone-specific alterations of liver sinusoidal endothelial cells in cirrhosis

T Su, Y Yang, S Lai, J Jeong, Y Jung… - Cellular and molecular …, 2021 - Elsevier
… We identified and mapped trascriptomic profiles of … range of nonhematopoietic cell types,
including subsets of ECs such as … (C, D) Immunofluorescence images of paraffin liver sections (…

A human liver cell atlas reveals heterogeneity and epithelial progenitors

N Aizarani, A Saviano, null Sagar, L Mailly, S Durand… - Nature, 2019 - nature.com
identified previously unknown subtypes of endothelial cells, … pathways between Kupffer cell
subsets and endothelial cells (… and immunohistochemistry revealed that cancer cells lose the …

[HTML][HTML] Capillarized liver sinusoidal endothelial cells undergo partial endothelial-mesenchymal transition to actively deposit sinusoidal ECM in liver fibrosis

B Ruan, JL Duan, H Xu, KS Tao, H Han… - Frontiers in Cell and …, 2021 - frontiersin.org
… a mouse model of liver fibrosis, while a subset of LSECs become … To prepare liver cryosections
for immunofluorescence … -seq analysis of physically isolated liver NPCs identifies four MF …

[PDF][PDF] Generation of functional liver sinusoidal endothelial cells from human pluripotent stem-cell-derived venous angioblasts

BK Gage, JC Liu, BT Innes, SA MacParland… - Cell Stem Cell, 2020 - cell.com
… (H–K) Immunofluorescence of cytospun day 8 CD34+ … fully mature or only a small subset
of cells expresses the gene. … genes that identified each of the 20 human liver cell types (Table …

[HTML][HTML] Molecular analysis of fetal and adult primary human liver sinusoidal endothelial cells: a comparison to other endothelial cells

MA Jamil, H Singer, R Al-Rifai, N Nüsgen… - International Journal of …, 2020 - mdpi.com
… to identify reliable methylation markers that specifically identify … Both fetal and adult LSECs
could be accurately identified … of cells were tested by flow cytometry and immunofluorescence

[HTML][HTML] Gene signatures detect damaged liver sinusoidal endothelial cells in chronic liver diseases

S Verhulst, EA van Os, V De Smet, N Eysackers… - Frontiers in …, 2021 - frontiersin.org
identified an additional cell population which was not present in the endothelial cell population
of healthy livers (… with hematoxylin eosin staining and immunofluorescence staining and …

Unraveling the transcriptional determinants of liver sinusoidal endothelial cell specialization

W de Haan, C Øie, M Benkheil… - … and Liver …, 2020 - journals.physiology.org
… of liver, heart, and brain endothelial cells (ECs), we established a 30-gene LSEC signature
comprising both established and newly identified … sectioned for immunofluorescence staining. …

[HTML][HTML] Angiodiversity and organotypic functions of sinusoidal endothelial cells

PS Koch, KH Lee, S Goerdt, HG Augustin - Angiogenesis, 2021 - Springer
… differentiated endothelial cells (EC) identifying differentially … of the liver is composed of liver
sinusoidal endothelial cells (… have also been proposed to give rise to a subset of liver EC […

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

P Ramachandran, R Dobie, JR Wilson-Kanamori… - Nature, 2019 - nature.com
human liver endothelial cells identified seven subpopulations (Fig. 4a). Classical endothelial
cell … Left, representative immunofluorescence images (n = 3) of collagen 1 (COL1; magenta)…