Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH
M Bravo, I Raurell, D Hide, A Fernández-Iglesias… - Scientific reports, 2019 - nature.com
… Our aim was to characterize liver sinusoidal endothelial cell (… (NO) production has been
identified as a major contributor to the … Recent publications described how two distinct subsets of …
identified as a major contributor to the … Recent publications described how two distinct subsets of …
The power of single‐cell analysis for the study of liver pathobiology
AL Chu, JD Schilling, KR King, AE Feldstein - Hepatology, 2021 - Wiley Online Library
… isolated and reclustered to identify underlying cell subsets. An … (27) RNA in situ hybridization
and immunohistochemistry … liver endothelial cells (LECs). They sequenced pairs of attached …
and immunohistochemistry … liver endothelial cells (LECs). They sequenced pairs of attached …
Liver injury in COVID-19 and IL-6 trans-signaling-induced endotheliopathy
MJ McConnell, N Kawaguchi, R Kondo, A Sonzogni… - Journal of …, 2021 - Elsevier
… 6 trans-signaling in liver sinusoidal endothelial cells (LSECs) … (ALT) were retrospectively
analyzed in a subset (n = 68), … platelets in the liver endothelium, immunofluorescence staining of …
analyzed in a subset (n = 68), … platelets in the liver endothelium, immunofluorescence staining of …
[HTML][HTML] Identification of lineage-specific transcription factors that prevent activation of hepatic stellate cells and promote fibrosis resolution
… Livers from mice were analyzed by immunohistochemistry. Quiescent, activated, and inactivated
HSCs were isolated from livers of … profiling identified peaks that were largely a subset of …
HSCs were isolated from livers of … profiling identified peaks that were largely a subset of …
[HTML][HTML] Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver
A Remmerie, L Martens, T Thoné, A Castoldi… - Immunity, 2020 - cell.com
… Here, we have employed cellular indexing of transcriptomes … and surface epitopes of CD45
+ cells in the livers of mice with MAFLD, … to the liver also differentiated into a distinct subset of …
+ cells in the livers of mice with MAFLD, … to the liver also differentiated into a distinct subset of …
Lineage tracing and single-cell analysis reveal proliferative Prom1+ tumour-propagating cells and their dynamic cellular transition during liver cancer progression
… Liver cancer stem cells are a unique subset of hepatocellular … Specifically, Prom1+ biliary
epithelial cells contributed to … , we examined the recipient livers by immunohistochemistry …
epithelial cells contributed to … , we examined the recipient livers by immunohistochemistry …
Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression
A Guillot, M Winkler, MS Afonso, A Aggarwal… - Hepatology, 2023 - journals.lww.com
… In a model of acute and targeted biliary epithelial cell death, … Inc.) multiplex
immunofluorescence technology as previously … a subset of markers. We therefore asked whether …
immunofluorescence technology as previously … a subset of markers. We therefore asked whether …
[HTML][HTML] Characterization of the liver immune microenvironment in liver biopsies from patients with chronic HBV infection
N van Buuren, R Ramirez, S Turner, D Chen, V Suri… - JHEP Reports, 2022 - Elsevier
… multiplex immunofluorescence and identified two different liver … as a marker for liver sinusoidal
endothelial cells, CD68 as a … In addition to traditional T-cell subsets, we were also able to …
endothelial cells, CD68 as a … In addition to traditional T-cell subsets, we were also able to …
Single cell RNA sequencing identifies subsets of hepatic stellate cells and myofibroblasts in liver fibrosis
O Krenkel, J Hundertmark, TP Ritz, R Weiskirchen… - Cells, 2019 - mdpi.com
… actin (α-SMA) immunohistochemistry on FFPE tissue sections (… , we excluded CD31 positive
endothelial cells as well as … These data indicate towards the existence of a distinct subset …
endothelial cells as well as … These data indicate towards the existence of a distinct subset …
[PDF][PDF] Identification of four immune subtypes characterized by distinct composition and functions of tumor microenvironment in intrahepatic cholangiocarcinoma
S Job, D Rapoud, A Dos Santos, P Gonzalez… - …, 2020 - Wiley Online Library
… and immunohistochemistry for CAF and immune cell markers… mal and those of epithelial
cell adhesion molecule in I1 … sequencing identifies distinct mutational patterns in liver fluke…
cell adhesion molecule in I1 … sequencing identifies distinct mutational patterns in liver fluke…