Targeting immunogenic cell death in cancer

A Ahmed, SWG Tait - Molecular oncology, 2020 - Wiley Online Library
immunogenic nature of necroptosis, necroptotic cells have been effectively used to induce
potent antitumor … In summary, robust antitumor immune responses require the efficient priming …

[HTML][HTML] Immunogenic cell death in cancer immunotherapy

M Choi, J Shin, CE Lee, JY Chung, M Kim, X Yan… - BMB …, 2023 - ncbi.nlm.nih.gov
… can improve anti-tumor immunity and outline clinical trials targeting ICD. … antitumor immunity.
We also introduce functional mechanisms of controllable lytic cell death such as necroptosis

Programmed cell death tunes tumor immunity

J Liu, M Hong, Y Li, D Chen, Y Wu, Y Hu - Frontiers in immunology, 2022 - frontiersin.org
… , non-immunogenic cell death such as apoptosis maintains the … Thus, triggering well-targeted
necroptosis of cancer cells … -induced necroptosis in T cells could refresh the anti-tumor

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

R Tang, J Xu, B Zhang, J Liu, C Liang, J Hua… - … hematology & oncology, 2020 - Springer
… of immunogenic cell death. Because most evidence is derived from studies using animal
and … Researchers unveiled ACSL4 as a target of caspase cleavage during bortezomib-induced

Necroptosis in immuno-oncology and cancer immunotherapy

J Sprooten, P De Wijngaert, I Vanmeerbeek, S Martin… - Cells, 2020 - mdpi.com
anticancer immunity. A large proportion of studies have emphasized the importance of
immunogenic apoptosis (ie, immunogenic cell deathanticancer lymphocytes via T cells targeting (…

Pyroptotic and necroptotic cell death in the tumor microenvironment and their potential to stimulate anti-tumor immune responses

A Scarpitta, UT Hacker, H Büning, O Boyer… - … in oncology, 2021 - frontiersin.org
… well as targeted anti-cancer approaches, those that induce a … Immunogenic cell death (ICD)
of tumor cell can be induced … therapy, photodynamic therapy, necroptosis, or pyroptosis) and …

Interrelation between programmed cell death and immunogenic cell death: take antitumor nanodrug as an example

Q Meng, B Ding, P Ma, J Lin - Small Methods, 2023 - Wiley Online Library
… traditional anticancer therapy, PDT has good tumor targeting … that led to cell membrane
rupture and cell necrosis due to the … by necrotic cells to cause anti-tumor immune effects. It was …

The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses

TL Aaes, P Vandenabeele - Cell Death & Differentiation, 2021 - nature.com
… (ICD) studies being apoptosis or necroptosis. We will … targeted by an antibody-drug (ie,
anthracycline) conjugate, which induced an immunogenic form of cell death in breast cancer

Cell death pathologies: targeting death pathways and the immune system for cancer therapy

F Pentimalli, S Grelli, N Di Daniele, G Melino… - Genes & Immunity, 2019 - nature.com
death pathways, such as ferroptosis, entosis, necroptosis and immunogenic cell death, each
… response, highlighting the potential of the combination of traditional anticancer therapy and …

Immunogenic cell death and role of nanomaterials serving as therapeutic vaccine for personalized cancer immunotherapy

E Catanzaro, O Feron, AG Skirtach… - … in immunology, 2022 - frontiersin.org
… in necroptosis-induced activation of antitumor immune … It has been shown that the
immunogenicity of necroptotic tumor cells is … to target several cell death modalities including …