Targeting immunogenic cell death in cancer
A Ahmed, SWG Tait - Molecular oncology, 2020 - Wiley Online Library
… immunogenic nature of necroptosis, necroptotic cells have been effectively used to induce
potent antitumor … In summary, robust antitumor immune responses require the efficient priming …
potent antitumor … In summary, robust antitumor immune responses require the efficient priming …
[HTML][HTML] Immunogenic cell death in cancer immunotherapy
M Choi, J Shin, CE Lee, JY Chung, M Kim, X Yan… - BMB …, 2023 - ncbi.nlm.nih.gov
… can improve anti-tumor immunity and outline clinical trials targeting ICD. … antitumor immunity.
We also introduce functional mechanisms of controllable lytic cell death such as necroptosis…
We also introduce functional mechanisms of controllable lytic cell death such as necroptosis…
Programmed cell death tunes tumor immunity
… , non-immunogenic cell death such as apoptosis maintains the … Thus, triggering well-targeted
necroptosis of cancer cells … -induced necroptosis in T cells could refresh the anti-tumor …
necroptosis of cancer cells … -induced necroptosis in T cells could refresh the anti-tumor …
Ferroptosis, necroptosis, and pyroptosis in anticancer immunity
R Tang, J Xu, B Zhang, J Liu, C Liang, J Hua… - … hematology & oncology, 2020 - Springer
… of immunogenic cell death. Because most evidence is derived from studies using animal
and … Researchers unveiled ACSL4 as a target of caspase cleavage during bortezomib-induced …
and … Researchers unveiled ACSL4 as a target of caspase cleavage during bortezomib-induced …
Necroptosis in immuno-oncology and cancer immunotherapy
J Sprooten, P De Wijngaert, I Vanmeerbeek, S Martin… - Cells, 2020 - mdpi.com
… anticancer immunity. A large proportion of studies have emphasized the importance of
immunogenic apoptosis (ie, immunogenic cell death … anticancer lymphocytes via T cells targeting (…
immunogenic apoptosis (ie, immunogenic cell death … anticancer lymphocytes via T cells targeting (…
Pyroptotic and necroptotic cell death in the tumor microenvironment and their potential to stimulate anti-tumor immune responses
… well as targeted anti-cancer approaches, those that induce a … Immunogenic cell death (ICD)
of tumor cell can be induced … therapy, photodynamic therapy, necroptosis, or pyroptosis) and …
of tumor cell can be induced … therapy, photodynamic therapy, necroptosis, or pyroptosis) and …
Interrelation between programmed cell death and immunogenic cell death: take antitumor nanodrug as an example
… traditional anticancer therapy, PDT has good tumor targeting … that led to cell membrane
rupture and cell necrosis due to the … by necrotic cells to cause anti-tumor immune effects. It was …
rupture and cell necrosis due to the … by necrotic cells to cause anti-tumor immune effects. It was …
The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses
TL Aaes, P Vandenabeele - Cell Death & Differentiation, 2021 - nature.com
… (ICD) studies being apoptosis or necroptosis. We will … targeted by an antibody-drug (ie,
anthracycline) conjugate, which induced an immunogenic form of cell death in breast cancer …
anthracycline) conjugate, which induced an immunogenic form of cell death in breast cancer …
Cell death pathologies: targeting death pathways and the immune system for cancer therapy
… death pathways, such as ferroptosis, entosis, necroptosis and immunogenic cell death, each
… response, highlighting the potential of the combination of traditional anticancer therapy and …
… response, highlighting the potential of the combination of traditional anticancer therapy and …
Immunogenic cell death and role of nanomaterials serving as therapeutic vaccine for personalized cancer immunotherapy
… in necroptosis-induced activation of antitumor immune … It has been shown that the
immunogenicity of necroptotic tumor cells is … to target several cell death modalities including …
immunogenicity of necroptotic tumor cells is … to target several cell death modalities including …